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Mammalian Phenotype Browser
Term Detail
MP term:atrioventricular septal defect
Synonym: atrioventricular canal defect
Synonym: Atrioventricular canal (endocardial cushion defect)
Synonym: AVC
Synonym: AVCD
Synonym: AVSD
Synonym: AV septal defect
Synonym: ECD
Synonym: endocardial cushion defect
MP id: MP:0010412
Alternate id: Fyler:1100
Definition: defects in the thin membranous structure between the right atrium and left ventricle that arise from faulty development of the embryonic endocardial cushions; the spectrum ranges from a primum atrial septal defect and cleft mitral valve, known as a partial atrioventricular septal defect (partial AVSD), to defects of both the primum atrial septum and inlet ventricular septum and the presence of a common atrioventricular valve, referred to as complete atrioventricular septal defect (complete AVSD)
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acardiovascular system phenotype
                is-aabnormal cardiovascular system morphology
                        is-aabnormal heart morphology
                                is-aabnormal heart septum morphology
                                        is-aabnormal atrioventricular septum morphology
                                                is-aatrioventricular septal defect [MP:0010412] (135 genotypes, 143 annotations)
                                                        is-acomplete atrioventricular septal defect +
                                                        is-aintermediate atrioventricular septal defect
                                                        is-apartial atrioventricular septal defect

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory