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Mammalian Phenotype Browser
Term Detail
MP term:abnormal circulating serum amyloid protein level
Synonym: abnormal SAA protein level
Synonym: abnormal Serum Amyloid A Protein level
MP id: MP:0010214
Definition: deviation from the normal blood levels of an acute-phase reaction protein that is a precursor to amyloid A protein; it is present in very high levels during acute inflammatory episodes, and is present in low concentrations in normal sera, but is found at higher concentrations in sera of older persons and in patients with amyloidosis
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating angiotensinogen level +
                                        is-aabnormal circulating antithrombin level +
                                        is-aabnormal circulating apolipoprotein level +
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating complement protein level +
                                        is-aabnormal circulating cytokine level +
                                        is-aabnormal circulating enzyme level +
                                        is-aabnormal circulating factor VIII level +
                                        is-aabnormal circulating ferritin level +
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating fibronectin level +
                                        is-aabnormal circulating prothrombin level +
                                        is-aabnormal circulating retinol binding protein level
                                        is-aabnormal circulating serum albumin level +
                                        is-aabnormal circulating serum amyloid protein level [MP:0010214] (11 genotypes, 11 annotations)
                                        is-aabnormal circulating thrombin level +
                                        is-aabnormal circulating total protein level +
                                        is-aabnormal circulating transferrin level +
                                        is-aabnormal glycosylated hemoglobin level +
                                        is-adecreased circulating ceruloplasmin level
                                        is-adecreased circulating haptoglobin level
                                        is-ahemoglobinemia
                                        is-aincreased circulating ceruloplasmin level
                                        is-aincreased circulating haptoglobin level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal acute phase protein level
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating serum amyloid protein level [MP:0010214] (11 genotypes, 11 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating angiotensinogen level +
                                        is-aabnormal circulating antithrombin level +
                                        is-aabnormal circulating apolipoprotein level +
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating complement protein level +
                                        is-aabnormal circulating cytokine level +
                                        is-aabnormal circulating enzyme level +
                                        is-aabnormal circulating factor VIII level +
                                        is-aabnormal circulating ferritin level +
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating fibronectin level +
                                        is-aabnormal circulating prothrombin level +
                                        is-aabnormal circulating retinol binding protein level
                                        is-aabnormal circulating serum albumin level +
                                        is-aabnormal circulating serum amyloid protein level [MP:0010214] (11 genotypes, 11 annotations)
                                        is-aabnormal circulating thrombin level +
                                        is-aabnormal circulating total protein level +
                                        is-aabnormal circulating transferrin level +
                                        is-aabnormal glycosylated hemoglobin level +
                                        is-adecreased circulating ceruloplasmin level
                                        is-adecreased circulating haptoglobin level
                                        is-ahemoglobinemia
                                        is-aincreased circulating ceruloplasmin level
                                        is-aincreased circulating haptoglobin level


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal acute phase protein level
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating serum amyloid protein level [MP:0010214] (11 genotypes, 11 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal innate immunity
                                is-aabnormal acute phase protein level
                                        is-aabnormal circulating C-reactive protein level
                                        is-aabnormal circulating fibrinogen level +
                                        is-aabnormal circulating serum amyloid protein level [MP:0010214] (11 genotypes, 11 annotations)

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory