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Mammalian Phenotype Browser
Term Detail
MP term:abnormal neural crest cell morphology
Synonym: abnormal NCC morphology
MP id: MP:0009845
Definition: any structural anomaly of the transient and highly migratory group of cells that delaminate in early embryonic development from the dorsal neural tube and give rise to a variety of differentiated cell types, including (1) the neurons and glial cells of the sensory, sympathetic, and parasympathetic nervous systems, (2) the epinephrine-producing (medulla) cells of the adrenal gland, (3) the pigment-containing cells of the epidermis, and (4) many of the skeletal and connective tissue components of the head
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal embryonic tissue morphology
                                is-aabnormal neural tube morphology/development
                                        is-aabnormal neural crest morphology
                                                is-aabnormal neural crest cell morphology [MP:0009845] (66 genotypes, 73 annotations)
                                                        is-aabnormal cardiac neural crest cell morphology +
                                                        is-aabnormal cranial neural crest cell morphology +
                                                        is-aabnormal enteric neural crest cell morphology +
                                                        is-aabnormal melanoblast morphology +
                                                        is-aabnormal trunk neural crest cell morphology
                                                        is-aabnormal vagal neural crest cell morphology +
                                                        is-adecreased neural crest cell number +
                                                        is-aimpaired neural crest cell differentiation +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal nervous system development
                                is-aabnormal neural tube morphology/development
                                        is-aabnormal neural crest morphology
                                                is-aabnormal neural crest cell morphology [MP:0009845] (66 genotypes, 73 annotations)
                                                        is-aabnormal cardiac neural crest cell morphology +
                                                        is-aabnormal cranial neural crest cell morphology +
                                                        is-aabnormal enteric neural crest cell morphology +
                                                        is-aabnormal melanoblast morphology +
                                                        is-aabnormal trunk neural crest cell morphology
                                                        is-aabnormal vagal neural crest cell morphology +
                                                        is-adecreased neural crest cell number +
                                                        is-aimpaired neural crest cell differentiation +

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory