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Mammalian Phenotype Browser
Term Detail
MP term:increased circulating interleukin-21 level
Synonym: increased circulating IL-21 level
Synonym: increased circulating IL21 level
MP id: MP:0009060
Definition: increase in the amount in the blood of a pleiotropic cytokine that regulates immunoglobulin production, plasma cell and Th17 T cell differentiation, CD8+ T cell expansion, and inhibits antigen presentation by dendritic cells
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-21 level
                                                                is-adecreased circulating interleukin-21 level
                                                                is-aincreased circulating interleukin-21 level [MP:0009060] (1 genotype, 1 annotation)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-21 level
                                                                is-adecreased circulating interleukin-21 level
                                                                is-aincreased circulating interleukin-21 level [MP:0009060] (1 genotype, 1 annotation)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal circulating cytokine level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-21 level
                                                                        is-adecreased circulating interleukin-21 level
                                                                        is-aincreased circulating interleukin-21 level [MP:0009060] (1 genotype, 1 annotation)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal interleukin level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-21 level
                                                                        is-adecreased circulating interleukin-21 level
                                                                        is-aincreased circulating interleukin-21 level [MP:0009060] (1 genotype, 1 annotation)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-21 level
                                                                is-adecreased circulating interleukin-21 level
                                                                is-aincreased circulating interleukin-21 level [MP:0009060] (1 genotype, 1 annotation)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal interleukin level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-21 level
                                                                is-adecreased circulating interleukin-21 level
                                                                is-aincreased circulating interleukin-21 level [MP:0009060] (1 genotype, 1 annotation)

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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory