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Mammalian Phenotype Browser
Term Detail
MP term:increased physiological sensitivity to xenobiotic
Synonym: decreased resistance to xenobiotics
Synonym: increased physiological sensitivity to xenobiotics
Synonym: increased susceptibility to xenobiotics
MP id: MP:0008873
Definition: decrease in the dose or concentration of a foreign compound required to induce a specific level of physiological response
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal physiological response to xenobiotic
                        is-aabnormal xenobiotic induced morbidity/mortality +
                        is-adecreased physiological sensitivity to xenobiotic +
                        is-aincreased physiological sensitivity to xenobiotic [MP:0008873] (361 genotypes, 372 annotations)
                                is-aincreased bronchoconstrictive response
                                is-aincreased incidence of tumors by chemical induction
                                is-aincreased susceptibility to neuronal excitotoxicity +
                                is-aincreased susceptibility to ototoxicity-induced hearing loss

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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory