About   Help   FAQ
Mammalian Phenotype Browser
Term Detail
MP term:chromosomal instability
Synonym: genomic instability
MP id: MP:0008866
Definition: abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal chromosome stability
                                is-achromosomal instability [MP:0008866] (209 genotypes, 235 annotations)
                                        is-achromosome breakage +
                                is-aincreased chromosomal stability

Back to entry page

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.08
The Jackson Laboratory