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Mammalian Phenotype Browser
Term Detail
MP term:abnormal cardiac epithelial to mesenchymal transition
Synonym: abnormal cardiac epithelial to mesenchymal transformation
Synonym: abnormal endocardial-mesenchymal transformation
MP id: MP:0008825
Definition: anomaly in the process by which endocardial cells of the atrioventricular canal or the outflow tract lose their epithelial characteristics, delaminate from the endocardial sheet, become migratory and invade the cardiac jelly, and develop mesenchymal characteristics eventually forming both the endocardial cushions required for septum and atrioventricular valve formation and the cushions of the outflow tract that form the conotruncal septum
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acardiovascular system phenotype
                is-aabnormal cardiovascular system morphology
                        is-aabnormal cardiovascular development
                                is-aabnormal angioblastic cord morphology
                                is-aabnormal aortic sac morphology +
                                is-aabnormal cardiac epithelial to mesenchymal transition [MP:0008825] (28 genotypes, 28 annotations)
                                is-aabnormal cardiac mesenchyme morphology
                                is-aabnormal cardiac neural crest cell morphology +
                                is-aabnormal cardiogenic mesoderm morphology
                                is-aabnormal cardiogenic plate morphology +
                                is-aabnormal heart development +
                                is-aabnormal outflow tract development +
                                is-aabnormal vascular development +

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory