| MP term: | abnormal cardiac epithelial to mesenchymal transition |
| Synonym: | abnormal cardiac epithelial to mesenchymal transformation |
| Synonym: | abnormal endocardial-mesenchymal transformation |
| MP id: | MP:0008825 |
| Definition: | anomaly in the process by which endocardial cells of the atrioventricular canal or the outflow tract lose their epithelial characteristics, delaminate from the endocardial sheet, become migratory and invade the cardiac jelly, and develop mesenchymal characteristics eventually forming both the endocardial cushions required for septum and atrioventricular valve formation and the cushions of the outflow tract that form the conotruncal septum |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cardiovascular system phenotypeabnormal cardiovascular system morphologyabnormal cardiovascular developmentabnormal cardiac epithelial to mesenchymal transition [MP:0008825] (28 genotypes, 28 annotations)abnormal cardiac mesenchyme morphologyabnormal heart development +abnormal outflow tract development +abnormal vascular development +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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