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Mammalian Phenotype Browser
Term Detail
MP term:increased susceptibility to endotoxin shock
Synonym: decreased resistance to endotoxic shock
Synonym: decreased resistance to endotoxin shock
Synonym: increased response to LPS induced shock
Synonym: increased sensitivity to endotoxic shock
Synonym: increased sensitivity to endotoxin shock
Synonym: increased susceptibility to endotoxic shock
MP id: MP:0008735
Definition: more than the expected early reaction of the microcirculation to endotoxins such as LPS, characterized by movement of fluid and leukocytes from the blood into extravascular tissues and often resulting in death
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal inflammatory response
                                is-aabnormal acute inflammation
                                        is-aincreased acute inflammation
                                                is-aincreased susceptibility to endotoxin shock [MP:0008735] (83 genotypes, 83 annotations)
                                                is-aincreased susceptibility to type I hypersensitivity reaction
                                                is-aincreased susceptibility to type II hypersensitivity reaction
                                                is-aincreased susceptibility to type III hypersensitivity reaction
                                                is-aincreased susceptibility to type IV hypersensitivity reaction


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal inflammatory response
                                is-aincreased inflammatory response
                                        is-aincreased acute inflammation
                                                is-aincreased susceptibility to endotoxin shock [MP:0008735] (83 genotypes, 83 annotations)
                                                is-aincreased susceptibility to type I hypersensitivity reaction
                                                is-aincreased susceptibility to type II hypersensitivity reaction
                                                is-aincreased susceptibility to type III hypersensitivity reaction
                                                is-aincreased susceptibility to type IV hypersensitivity reaction

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory