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Mammalian Phenotype Browser
Term Detail
MP term:increased interleukin-12 secretion
Synonym: increased cytotoxic lymphocyte maturation factor secretion
Synonym: increased IL-12 p70 secretion
Synonym: increased IL-12 secretion
Synonym: increased IL12 secretion
Synonym: increased interleukin-12 p70 secretion
Synonym: increased natural killer cell stimulatory factor secretion
MP id: MP:0008663
Definition: increase in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine secretion
                                        is-aabnormal interleukin secretion
                                                is-aabnormal interleukin-12 secretion
                                                        is-aabnormal interleukin-12a secretion +
                                                        is-adecreased interleukin-12 secretion
                                                        is-aincreased interleukin-12 secretion [MP:0008663] (35 genotypes, 35 annotations)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory