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Mammalian Phenotype Browser
Term Detail
MP term:decreased interleukin-1 beta secretion
Synonym: decreased catabloin secretion
Synonym: decreased IL-1 beta secretion
Synonym: decreased Il1b secretion
Synonym: decreased IL-1b secretion
Synonym: reduced catabloin secretion
Synonym: reduced IL-1 beta secretion
Synonym: reduced Il1b secretion
Synonym: reduced IL-1b secretion
MP id: MP:0008658
Definition: reduction in the production or release of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine secretion
                                        is-aabnormal interleukin secretion
                                                is-aabnormal interleukin-1 secretion
                                                        is-aabnormal interleukin-1 beta secretion
                                                                is-adecreased interleukin-1 beta secretion [MP:0008658] (86 genotypes, 86 annotations)
                                                                is-aincreased interleukin-1 beta secretion

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MGI 6.08
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