| MP term: | decreased interleukin-1 beta secretion |
| Synonym: | decreased catabloin secretion |
| Synonym: | decreased IL-1 beta secretion |
| Synonym: | decreased Il1b secretion |
| Synonym: | decreased IL-1b secretion |
| Synonym: | reduced catabloin secretion |
| Synonym: | reduced IL-1 beta secretion |
| Synonym: | reduced Il1b secretion |
| Synonym: | reduced IL-1b secretion |
| MP id: | MP:0008658 |
| Definition: | reduction in the production or release of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
immune system phenotypeabnormal immune system physiologyabnormal immune serum protein physiologyabnormal cytokine secretionabnormal interleukin secretionabnormal interleukin-1 secretionabnormal interleukin-1 beta secretiondecreased interleukin-1 beta secretion [MP:0008658] (59 genotypes, 59 annotations)increased interleukin-1 beta secretionMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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