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Term Detail
MP term:decreased circulating interleukin-1 beta level
Synonym: decreased circulating catabloin level
Synonym: decreased circulating IL-1 beta level
Synonym: decreased circulating Il1b level
Synonym: decreased circulating IL-1b level
Synonym: reduced circulating catabloin level
Synonym: reduced circulating IL-1 beta level
Synonym: reduced circulating Il1b level
Synonym: reduced circulating IL-1b level
MP id: MP:0008642
Definition: reduction in the amount in the blood of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 beta level
                                                                        is-adecreased circulating interleukin-1 beta level [MP:0008642] (30 genotypes, 30 annotations)
                                                                        is-aincreased circulating interleukin-1 beta level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 beta level
                                                                        is-adecreased circulating interleukin-1 beta level [MP:0008642] (30 genotypes, 30 annotations)
                                                                        is-aincreased circulating interleukin-1 beta level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal circulating cytokine level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-1 level
                                                                        is-aabnormal circulating interleukin-1 beta level
                                                                                is-adecreased circulating interleukin-1 beta level [MP:0008642] (30 genotypes, 30 annotations)
                                                                                is-aincreased circulating interleukin-1 beta level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal interleukin level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-1 level
                                                                        is-aabnormal circulating interleukin-1 beta level
                                                                                is-adecreased circulating interleukin-1 beta level [MP:0008642] (30 genotypes, 30 annotations)
                                                                                is-aincreased circulating interleukin-1 beta level


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 beta level
                                                                        is-adecreased circulating interleukin-1 beta level [MP:0008642] (30 genotypes, 30 annotations)
                                                                        is-aincreased circulating interleukin-1 beta level


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal interleukin level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 beta level
                                                                        is-adecreased circulating interleukin-1 beta level [MP:0008642] (30 genotypes, 30 annotations)
                                                                        is-aincreased circulating interleukin-1 beta level

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory