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Term Detail
MP term:decreased circulating interleukin-1 alpha level
Synonym: decreased circulating hematopoietin-1 level
Synonym: decreased circulating IL-1a level
Synonym: decreased circulating IL1a level
Synonym: decreased circulating IL-1alpha level
Synonym: decreased circulating IL1 alpha level
Synonym: reduced circulating hematopoietin-1 level
Synonym: reduced circulating IL-1a level
Synonym: reduced circulating IL1a level
Synonym: reduced circulating IL-1alpha level
Synonym: reduced circulating IL1 alpha level
MP id: MP:0008639
Definition: reduction in the amount in the blood of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 alpha level
                                                                        is-adecreased circulating interleukin-1 alpha level [MP:0008639] (11 genotypes, 11 annotations)
                                                                        is-aincreased circulating interleukin-1 alpha level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 alpha level
                                                                        is-adecreased circulating interleukin-1 alpha level [MP:0008639] (11 genotypes, 11 annotations)
                                                                        is-aincreased circulating interleukin-1 alpha level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal circulating cytokine level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-1 level
                                                                        is-aabnormal circulating interleukin-1 alpha level
                                                                                is-adecreased circulating interleukin-1 alpha level [MP:0008639] (11 genotypes, 11 annotations)
                                                                                is-aincreased circulating interleukin-1 alpha level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal interleukin level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-1 level
                                                                        is-aabnormal circulating interleukin-1 alpha level
                                                                                is-adecreased circulating interleukin-1 alpha level [MP:0008639] (11 genotypes, 11 annotations)
                                                                                is-aincreased circulating interleukin-1 alpha level


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 alpha level
                                                                        is-adecreased circulating interleukin-1 alpha level [MP:0008639] (11 genotypes, 11 annotations)
                                                                        is-aincreased circulating interleukin-1 alpha level


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal interleukin level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-1 level
                                                                is-aabnormal circulating interleukin-1 alpha level
                                                                        is-adecreased circulating interleukin-1 alpha level [MP:0008639] (11 genotypes, 11 annotations)
                                                                        is-aincreased circulating interleukin-1 alpha level

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory