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Term Detail
MP term:increased circulating interleukin-10 level
Synonym: increased circulating CSIF-10 level
Synonym: increased circulating cytokine synthesis inhibitory factor level
Synonym: increased circulating IL-10 level
Synonym: increased circulating IL10 level
MP id: MP:0008593
Definition: increase in the amount in the blood of a cytokine produced by a variety of cell types, including T-cells, monocytes, dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-10 level
                                                                is-adecreased circulating interleukin-10 level
                                                                is-aincreased circulating interleukin-10 level [MP:0008593] (26 genotypes, 26 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal circulating protein level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-10 level
                                                                is-adecreased circulating interleukin-10 level
                                                                is-aincreased circulating interleukin-10 level [MP:0008593] (26 genotypes, 26 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal circulating cytokine level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-10 level
                                                                        is-adecreased circulating interleukin-10 level
                                                                        is-aincreased circulating interleukin-10 level [MP:0008593] (26 genotypes, 26 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal protein level
                                is-aabnormal intercellular signaling peptide or protein level
                                        is-aabnormal cytokine level
                                                is-aabnormal interleukin level
                                                        is-aabnormal circulating interleukin level
                                                                is-aabnormal circulating interleukin-10 level
                                                                        is-adecreased circulating interleukin-10 level
                                                                        is-aincreased circulating interleukin-10 level [MP:0008593] (26 genotypes, 26 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal circulating cytokine level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-10 level
                                                                is-adecreased circulating interleukin-10 level
                                                                is-aincreased circulating interleukin-10 level [MP:0008593] (26 genotypes, 26 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune serum protein physiology
                                is-aabnormal cytokine level
                                        is-aabnormal interleukin level
                                                is-aabnormal circulating interleukin level
                                                        is-aabnormal circulating interleukin-10 level
                                                                is-adecreased circulating interleukin-10 level
                                                                is-aincreased circulating interleukin-10 level [MP:0008593] (26 genotypes, 26 annotations)

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory