| MP term: | decreased tumor necrosis factor secretion |
| Synonym: | decreased cachectin secretion |
| Synonym: | decreased TNFA secretion |
| Synonym: | decreased TNF secretion |
| Synonym: | decreased tumor necrosis factor alpha secretion |
| Synonym: | reduced cachectin secretion |
| Synonym: | reduced TNFA secretion |
| Synonym: | reduced TNF secretion |
| Synonym: | reduced tumor necrosis factor alpha secretion |
| MP id: | MP:0008561 |
| Definition: | reduction in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
immune system phenotypeabnormal immune system physiologyabnormal immune serum protein physiologyabnormal cytokine secretionabnormal tumor necrosis factor secretiondecreased tumor necrosis factor secretion [MP:0008561] (152 genotypes, 152 annotations)increased tumor necrosis factor secretionMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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