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Mammalian Phenotype Browser
Term Detail
MP term:increased cellular sensitivity to oxidative stress
Synonym: decreased cellular resistance to oxidative stress
Synonym: increased cellular susceptibility to oxidative stress
MP id: MP:0008412
Definition: greater incidence of cell death or enhanced production of reactive oxygen species after exposure to a variety of stress conditions including ionizing radiation, exposure to xenobiotics, inflammation, and phagocytosis
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-aabnormal induced cell death
                                        is-aincreased sensitivity to induced cell death
                                                is-aincreased cellular sensitivity to alkylating agents +
                                                is-aincreased cellular sensitivity to ionizing radiation +
                                                is-aincreased cellular sensitivity to oxidative stress [MP:0008412] (45 genotypes, 51 annotations)
                                                        is-aincreased cellular sensitivity to hydrogen peroxide
                                                is-aincreased cellular sensitivity to ultraviolet irradiation

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory