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Mammalian Phenotype Browser
Term Detail
MP term:abnormal osteoclast differentiation
Synonym: abnormal chondrocyte differentiation
Synonym: abnormal osteoclast formation
Synonym: abnormal osteophage formation
MP id: MP:0008396
Alternate id: MP:0000059
Definition: atypical production of or inability to produce the specialized phagocytic cells associated with the absorption and removal of the mineralized matrix of bone tissue
Number of paths to term: 8

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell differentiation
                                is-aabnormal airway basal cell differentiation
                                is-aabnormal Bergmann glial cell differentiation
                                is-aabnormal dendritic cell differentiation +
                                is-aabnormal enterocyte differentiation
                                is-aabnormal fat cell differentiation +
                                is-aabnormal granulocyte differentiation +
                                is-aabnormal keratinocyte differentiation +
                                is-aabnormal megakaryocyte differentiation
                                is-aabnormal mesenchymal cell differentiation involved in lung development
                                is-aabnormal mononuclear cell differentiation +
                                is-aabnormal myoblast differentiation
                                is-aabnormal myofibroblast differentiation +
                                is-aabnormal neuron differentiation +
                                is-aabnormal organ of Corti supporting cell differentiation +
                                is-aabnormal osteoblast differentiation +
                                is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)
                                is-aabnormal pancreatic alpha cell differentiation
                                is-aabnormal pancreatic beta cell differentiation
                                is-aabnormal pancreatic delta cell differentiation
                                is-aabnormal pancreatic epsilon cell differentiation
                                is-aabnormal PP cell differentiation
                                is-aabnormal vascular endothelial cell differentiation
                                is-aimpaired granulosa cell differentiation +
                                is-aimpaired luteal cell differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology
                                                                        is-aabnormal osteoclast morphology
                                                                                is-aabnormal osteoclast cell number +
                                                                                is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal phagocyte morphology
                                                                is-aabnormal mononuclear phagocyte morphology
                                                                        is-aabnormal macrophage morphology
                                                                                is-aabnormal osteoclast morphology
                                                                                        is-aabnormal osteoclast cell number +
                                                                                        is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal mononuclear phagocyte morphology
                                                        is-aabnormal macrophage morphology
                                                                is-aabnormal osteoclast morphology
                                                                        is-aabnormal osteoclast cell number +
                                                                        is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal phagocyte morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology
                                                                        is-aabnormal osteoclast morphology
                                                                                is-aabnormal osteoclast cell number +
                                                                                is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal macrophage morphology
                                                is-aabnormal osteoclast morphology
                                                        is-aabnormal osteoclast cell number +
                                                        is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)


mammalian phenotype
        is-askeleton phenotype
                is-aabnormal skeleton morphology
                        is-aabnormal bone structure
                                is-aabnormal osteoclast morphology
                                        is-aabnormal osteoclast cell number +
                                        is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)


mammalian phenotype
        is-askeleton phenotype
                is-aabnormal skeleton morphology
                        is-aabnormal skeleton development
                                is-aabnormal bone marrow development
                                is-aabnormal cartilage development +
                                is-aabnormal epiphyseal plate morphology +
                                is-aabnormal fontanelle morphology +
                                is-aabnormal long bone epiphysis morphology +
                                is-aabnormal ossification involved in bone maturation +
                                is-aabnormal osteoblast differentiation +
                                is-aabnormal osteoclast differentiation [MP:0008396] (107 genotypes, 107 annotations)
                                is-aabnormal osteoid morphology +
                                is-aabnormal rib development
                                is-aabnormal sclerotome morphology +
                                is-aabnormal vertebrae development +
                                is-achondrodystrophy

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory