| MP term: | abnormal osteoclast differentiation |
| Synonym: | abnormal osteoclast formation |
| Synonym: | abnormal osteophage formation |
| MP id: | MP:0008396 |
| Alternate id: | MP:0000059 |
| Definition: | atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix |
| Number of paths to term: | 10 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal airway basal cell differentiationabnormal Bergmann glial cell differentiationabnormal dendritic cell differentiation +abnormal enterocyte differentiationabnormal fat cell differentiation +abnormal granulocyte differentiation +abnormal keratinocyte differentiation +abnormal megakaryocyte differentiationabnormal mesenchymal cell differentiation involved in lung developmentabnormal mononuclear cell differentiation +abnormal myoblast differentiationabnormal neuron differentiation +abnormal organ of Corti supporting cell differentiation +abnormal osteoblast differentiation +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)abnormal pancreatic alpha cell differentiationabnormal pancreatic beta cell differentiationabnormal pancreatic delta cell differentiationabnormal pancreatic epsilon cell differentiationabnormal PP cell differentiationabnormal vascular endothelial cell differentiationimpaired granulosa cell differentiation +impaired luteal cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal professional antigen presenting cell morphologyabnormal macrophage morphologyabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)skeleton phenotypeabnormal skeleton morphologyabnormal bone structureabnormal osteoclast morphologyabnormal osteoclast cell number +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)skeleton phenotypeabnormal skeleton morphologyabnormal skeleton developmentabnormal bone marrow developmentabnormal cartilage development +abnormal epiphyseal plate morphology +abnormal fontanelle morphology +abnormal long bone epiphysis morphology +abnormal ossification involved in bone maturation +abnormal osteoblast differentiation +abnormal osteoclast differentiation [MP:0008396] (100 genotypes, 100 annotations)abnormal osteoid morphology +abnormal rib developmentabnormal sclerotome morphology +abnormal vertebrae development +chondrodystrophyMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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