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Mammalian Phenotype Browser
Term Detail
MP term:abnormal osteoblast differentiation
Synonym: abnormal osteoblast formation
Synonym: abnormal osteoplast formation
MP id: MP:0008395
Alternate id: MP:0005008
Definition: atypical production of or inability to produce skeletogenic cells that secrete osteoid, are capable of producing mineralized (hydroxyapatite) matrix, are located adjacent to or within osteoid tissue, and arise from the transformation of a preosteoblast cell
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell differentiation
                                is-aabnormal airway basal cell differentiation
                                is-aabnormal Bergmann glial cell differentiation
                                is-aabnormal dendritic cell differentiation +
                                is-aabnormal enterocyte differentiation
                                is-aabnormal fat cell differentiation +
                                is-aabnormal granulocyte differentiation +
                                is-aabnormal keratinocyte differentiation +
                                is-aabnormal megakaryocyte differentiation
                                is-aabnormal mesenchymal cell differentiation involved in lung development
                                is-aabnormal mononuclear cell differentiation +
                                is-aabnormal myoblast differentiation
                                is-aabnormal myofibroblast differentiation +
                                is-aabnormal neuron differentiation +
                                is-aabnormal organ of Corti supporting cell differentiation +
                                is-aabnormal osteoblast differentiation [MP:0008395] (76 genotypes, 77 annotations)
                                        is-aenhanced osteoblast differentiation
                                        is-aimpaired osteoblast differentiation +
                                is-aabnormal osteoclast differentiation
                                is-aabnormal pancreatic alpha cell differentiation
                                is-aabnormal pancreatic beta cell differentiation
                                is-aabnormal pancreatic delta cell differentiation
                                is-aabnormal pancreatic epsilon cell differentiation
                                is-aabnormal PP cell differentiation
                                is-aabnormal vascular endothelial cell differentiation
                                is-aimpaired granulosa cell differentiation +
                                is-aimpaired luteal cell differentiation
                                is-aimpaired neural crest cell differentiation +


mammalian phenotype
        is-askeleton phenotype
                is-aabnormal skeleton morphology
                        is-aabnormal bone structure
                                is-aabnormal osteoblast morphology
                                        is-aabnormal osteoblast cell number +
                                        is-aabnormal osteoblast differentiation [MP:0008395] (76 genotypes, 77 annotations)
                                                is-aenhanced osteoblast differentiation
                                                is-aimpaired osteoblast differentiation +
                                        is-aabnormal osteocyte morphology


mammalian phenotype
        is-askeleton phenotype
                is-aabnormal skeleton morphology
                        is-aabnormal skeleton development
                                is-aabnormal bone marrow development
                                is-aabnormal cartilage development +
                                is-aabnormal epiphyseal plate morphology +
                                is-aabnormal fontanelle morphology +
                                is-aabnormal long bone epiphysis morphology +
                                is-aabnormal ossification involved in bone maturation +
                                is-aabnormal osteoblast differentiation [MP:0008395] (76 genotypes, 77 annotations)
                                        is-aenhanced osteoblast differentiation
                                        is-aimpaired osteoblast differentiation +
                                is-aabnormal osteoclast differentiation
                                is-aabnormal osteoid morphology +
                                is-aabnormal rib development
                                is-aabnormal sclerotome morphology +
                                is-aabnormal vertebrae development +
                                is-achondrodystrophy

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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory