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Mammalian Phenotype Browser
Term Detail
MP term:abnormal metallophilic macrophage morphology
Synonym: abnormal marginal metallophilic macrophage
Synonym: abnormal MOMA-1 positive cells
Synonym: abnormal splenic marginal metallophilic macrophages
Synonym: abnormal splenic metallophilic macrophage morphology
MP id: MP:0008241
Definition: any structural anomaly of the macrophage cells that surround the white pulp of the spleen, adjacent to the marginal sinus
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology
                                                                        is-aabnormal alveolar macrophage morphology
                                                                        is-aabnormal Kupffer cell morphology
                                                                        is-aabnormal macrophage cell number +
                                                                        is-aabnormal macrophage derived foam cell morphology +
                                                                        is-aabnormal macrophage differentiation
                                                                        is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                                                        is-aabnormal microglial cell morphology +
                                                                        is-aabnormal osteoclast morphology +
                                                                        is-aabnormal peritoneal macrophage morphology
                                                                        is-aabnormal perivascular macrophage morphology
                                                                        is-aabnormal spleen marginal zone macrophage morphology
                                                                        is-adecreased macrophage cell number +
                                                                        is-aincreased macrophage cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal phagocyte morphology
                                                                is-aabnormal mononuclear phagocyte morphology
                                                                        is-aabnormal macrophage morphology
                                                                                is-aabnormal alveolar macrophage morphology
                                                                                is-aabnormal Kupffer cell morphology
                                                                                is-aabnormal macrophage cell number +
                                                                                is-aabnormal macrophage derived foam cell morphology +
                                                                                is-aabnormal macrophage differentiation
                                                                                is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                                                                is-aabnormal microglial cell morphology +
                                                                                is-aabnormal osteoclast morphology +
                                                                                is-aabnormal peritoneal macrophage morphology
                                                                                is-aabnormal perivascular macrophage morphology
                                                                                is-aabnormal spleen marginal zone macrophage morphology
                                                                                is-adecreased macrophage cell number +
                                                                                is-aincreased macrophage cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal spleen morphology
                                is-aabnormal spleen white pulp morphology
                                        is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                        is-aabnormal spleen B cell follicle morphology +
                                        is-aabnormal spleen central arteriole morphology
                                        is-aabnormal spleen marginal sinus morphology
                                        is-aabnormal spleen marginal zone morphology +
                                        is-aabnormal spleen periarteriolar lymphoid sheath morphology
                                        is-aabsent spleen white pulp
                                        is-adecreased spleen white pulp amount
                                        is-aincreased spleen white pulp amount
                                        is-aintermingled spleen red and white pulp


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal mononuclear phagocyte morphology
                                                        is-aabnormal macrophage morphology
                                                                is-aabnormal alveolar macrophage morphology
                                                                is-aabnormal Kupffer cell morphology
                                                                is-aabnormal macrophage cell number +
                                                                is-aabnormal macrophage derived foam cell morphology +
                                                                is-aabnormal macrophage differentiation
                                                                is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                                                is-aabnormal microglial cell morphology +
                                                                is-aabnormal osteoclast morphology +
                                                                is-aabnormal peritoneal macrophage morphology
                                                                is-aabnormal perivascular macrophage morphology
                                                                is-aabnormal spleen marginal zone macrophage morphology
                                                                is-adecreased macrophage cell number +
                                                                is-aincreased macrophage cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal phagocyte morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology
                                                                        is-aabnormal alveolar macrophage morphology
                                                                        is-aabnormal Kupffer cell morphology
                                                                        is-aabnormal macrophage cell number +
                                                                        is-aabnormal macrophage derived foam cell morphology +
                                                                        is-aabnormal macrophage differentiation
                                                                        is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                                                        is-aabnormal microglial cell morphology +
                                                                        is-aabnormal osteoclast morphology +
                                                                        is-aabnormal peritoneal macrophage morphology
                                                                        is-aabnormal perivascular macrophage morphology
                                                                        is-aabnormal spleen marginal zone macrophage morphology
                                                                        is-adecreased macrophage cell number +
                                                                        is-aincreased macrophage cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal macrophage morphology
                                                is-aabnormal alveolar macrophage morphology
                                                is-aabnormal Kupffer cell morphology
                                                is-aabnormal macrophage cell number +
                                                is-aabnormal macrophage derived foam cell morphology +
                                                is-aabnormal macrophage differentiation
                                                is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                                is-aabnormal microglial cell morphology +
                                                is-aabnormal osteoclast morphology +
                                                is-aabnormal peritoneal macrophage morphology
                                                is-aabnormal perivascular macrophage morphology
                                                is-aabnormal spleen marginal zone macrophage morphology
                                                is-adecreased macrophage cell number +
                                                is-aincreased macrophage cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system organ morphology
                                is-aabnormal spleen morphology
                                        is-aabnormal spleen white pulp morphology
                                                is-aabnormal metallophilic macrophage morphology [MP:0008241] (15 genotypes, 15 annotations)
                                                is-aabnormal spleen B cell follicle morphology +
                                                is-aabnormal spleen central arteriole morphology
                                                is-aabnormal spleen marginal sinus morphology
                                                is-aabnormal spleen marginal zone morphology +
                                                is-aabnormal spleen periarteriolar lymphoid sheath morphology
                                                is-aabsent spleen white pulp
                                                is-adecreased spleen white pulp amount
                                                is-aincreased spleen white pulp amount
                                                is-aintermingled spleen red and white pulp

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory