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Mammalian Phenotype Browser
Term Detail
MP term:abnormal Langerhans cell morphology
MP id: MP:0008117
Definition: any structural anomaly of a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal dendritic cell morphology
                                                        is-aabnormal myeloid dendritic cell morphology
                                                                is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                        is-adecreased Langerhans cell number +
                                                                is-aabnormal myeloid dendritic cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal myeloid dendritic cell morphology
                                                                        is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                                is-adecreased Langerhans cell number +
                                                                        is-aabnormal myeloid dendritic cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal phagocyte morphology
                                                                is-aabnormal mononuclear phagocyte morphology
                                                                        is-aabnormal myeloid dendritic cell morphology
                                                                                is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                                        is-adecreased Langerhans cell number +
                                                                                is-aabnormal myeloid dendritic cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal dendritic cell morphology
                                                is-aabnormal myeloid dendritic cell morphology
                                                        is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                is-adecreased Langerhans cell number +
                                                        is-aabnormal myeloid dendritic cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal mononuclear phagocyte morphology
                                                        is-aabnormal myeloid dendritic cell morphology
                                                                is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                        is-adecreased Langerhans cell number +
                                                                is-aabnormal myeloid dendritic cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal phagocyte morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal myeloid dendritic cell morphology
                                                                        is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                                is-adecreased Langerhans cell number +
                                                                        is-aabnormal myeloid dendritic cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal dendritic cell morphology
                                                is-aabnormal myeloid dendritic cell morphology
                                                        is-aabnormal Langerhans cell morphology [MP:0008117] (28 genotypes, 34 annotations)
                                                                is-adecreased Langerhans cell number +
                                                        is-aabnormal myeloid dendritic cell number +

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory