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Mammalian Phenotype Browser
Term Detail
MP term:abnormal CD4-positive, alpha beta T cell number
Synonym: abnormal CD4-positive T cell number
Synonym: abnormal CD4+ T cell number
MP id: MP:0008073
Definition: anomaly in the number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production
Number of paths to term: 11

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal hematopoietic cell number
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-aabnormal alpha-beta T cell number
                                                                                is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                        is-aabnormal T follicular helper cell number +
                                                                                        is-aabnormal T-helper 1 cell number +
                                                                                        is-aabnormal T-helper 17 cell number +
                                                                                        is-aabnormal T-helper 2 cell number +
                                                                                        is-adecreased CD4-positive, alpha beta T cell number +
                                                                                        is-aincreased CD4-positive, alpha beta T cell number +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal leukocyte cell number
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-aabnormal alpha-beta T cell number
                                                                                is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                        is-aabnormal T follicular helper cell number +
                                                                                        is-aabnormal T-helper 1 cell number +
                                                                                        is-aabnormal T-helper 17 cell number +
                                                                                        is-aabnormal T-helper 2 cell number +
                                                                                        is-adecreased CD4-positive, alpha beta T cell number +
                                                                                        is-aincreased CD4-positive, alpha beta T cell number +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphocyte cell number
                                                                        is-aabnormal T cell number
                                                                                is-aabnormal alpha-beta T cell number
                                                                                        is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                                is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                                is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                                is-aabnormal T follicular helper cell number +
                                                                                                is-aabnormal T-helper 1 cell number +
                                                                                                is-aabnormal T-helper 17 cell number +
                                                                                                is-aabnormal T-helper 2 cell number +
                                                                                                is-adecreased CD4-positive, alpha beta T cell number +
                                                                                                is-aincreased CD4-positive, alpha beta T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                        is-adecreased alpha-beta T cell number +
                                                                                        is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal alpha-beta T cell morphology
                                                                                is-aabnormal alpha-beta T cell number
                                                                                        is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                                is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                                is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                                is-aabnormal T follicular helper cell number +
                                                                                                is-aabnormal T-helper 1 cell number +
                                                                                                is-aabnormal T-helper 17 cell number +
                                                                                                is-aabnormal T-helper 2 cell number +
                                                                                                is-adecreased CD4-positive, alpha beta T cell number +
                                                                                                is-aincreased CD4-positive, alpha beta T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                        is-adecreased alpha-beta T cell number +
                                                                                        is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal effector T cell morphology
                                                                                is-aabnormal CD4-positive, alpha beta T cell morphology
                                                                                        is-aabnormal CD4-positive helper T cell morphology +
                                                                                        is-aabnormal CD4-positive T cell differentiation +
                                                                                        is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                                is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                                is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                                is-aabnormal T follicular helper cell number +
                                                                                                is-aabnormal T-helper 1 cell number +
                                                                                                is-aabnormal T-helper 17 cell number +
                                                                                                is-aabnormal T-helper 2 cell number +
                                                                                                is-adecreased CD4-positive, alpha beta T cell number +
                                                                                                is-aincreased CD4-positive, alpha beta T cell number +
                                                                                        is-aabnormal CD4-positive, alpha-beta intraepithelial T cell morphology
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell morphology +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal T cell number
                                                                                is-aabnormal alpha-beta T cell number
                                                                                        is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                                is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                                is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                                is-aabnormal T follicular helper cell number +
                                                                                                is-aabnormal T-helper 1 cell number +
                                                                                                is-aabnormal T-helper 17 cell number +
                                                                                                is-aabnormal T-helper 2 cell number +
                                                                                                is-adecreased CD4-positive, alpha beta T cell number +
                                                                                                is-aincreased CD4-positive, alpha beta T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                        is-adecreased alpha-beta T cell number +
                                                                                        is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal leukocyte cell number
                                                is-aabnormal lymphocyte cell number
                                                        is-aabnormal T cell number
                                                                is-aabnormal alpha-beta T cell number
                                                                        is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                is-aabnormal T follicular helper cell number +
                                                                                is-aabnormal T-helper 1 cell number +
                                                                                is-aabnormal T-helper 17 cell number +
                                                                                is-aabnormal T-helper 2 cell number +
                                                                                is-adecreased CD4-positive, alpha beta T cell number +
                                                                                is-aincreased CD4-positive, alpha beta T cell number +
                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                        is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                        is-adecreased alpha-beta T cell number +
                                                                        is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphocyte cell number
                                                                is-aabnormal T cell number
                                                                        is-aabnormal alpha-beta T cell number
                                                                                is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                        is-aabnormal T follicular helper cell number +
                                                                                        is-aabnormal T-helper 1 cell number +
                                                                                        is-aabnormal T-helper 17 cell number +
                                                                                        is-aabnormal T-helper 2 cell number +
                                                                                        is-adecreased CD4-positive, alpha beta T cell number +
                                                                                        is-aincreased CD4-positive, alpha beta T cell number +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal alpha-beta T cell morphology
                                                                        is-aabnormal alpha-beta T cell number
                                                                                is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                        is-aabnormal T follicular helper cell number +
                                                                                        is-aabnormal T-helper 1 cell number +
                                                                                        is-aabnormal T-helper 17 cell number +
                                                                                        is-aabnormal T-helper 2 cell number +
                                                                                        is-adecreased CD4-positive, alpha beta T cell number +
                                                                                        is-aincreased CD4-positive, alpha beta T cell number +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-aincreased alpha-beta T cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal effector T cell morphology
                                                                        is-aabnormal CD4-positive, alpha beta T cell morphology
                                                                                is-aabnormal CD4-positive helper T cell morphology +
                                                                                is-aabnormal CD4-positive T cell differentiation +
                                                                                is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                        is-aabnormal T follicular helper cell number +
                                                                                        is-aabnormal T-helper 1 cell number +
                                                                                        is-aabnormal T-helper 17 cell number +
                                                                                        is-aabnormal T-helper 2 cell number +
                                                                                        is-adecreased CD4-positive, alpha beta T cell number +
                                                                                        is-aincreased CD4-positive, alpha beta T cell number +
                                                                                is-aabnormal CD4-positive, alpha-beta intraepithelial T cell morphology
                                                                                is-aabnormal CD4-positive, alpha-beta memory T cell morphology +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal T cell number
                                                                        is-aabnormal alpha-beta T cell number
                                                                                is-aabnormal CD4-positive, alpha beta T cell number [MP:0008073] (727 genotypes, 791 annotations)
                                                                                        is-aabnormal CD4-positive, alpha-beta memory T cell number +
                                                                                        is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                        is-aabnormal KLRG1+ CD4 alpha beta T cell number +
                                                                                        is-aabnormal T follicular helper cell number +
                                                                                        is-aabnormal T-helper 1 cell number +
                                                                                        is-aabnormal T-helper 17 cell number +
                                                                                        is-aabnormal T-helper 2 cell number +
                                                                                        is-adecreased CD4-positive, alpha beta T cell number +
                                                                                        is-aincreased CD4-positive, alpha beta T cell number +
                                                                                is-aabnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
                                                                                is-aabnormal CD8-positive, alpha-beta T cell number +
                                                                                is-adecreased alpha-beta T cell number +
                                                                                is-aincreased alpha-beta T cell number +

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory