| MP term: | increased susceptibility to type III hypersensitivity reaction |
| Synonym: | decreased resistance to immune complex mediated hypersensitivity |
| Synonym: | decreased resistance to type III hypersensitivity reaction |
| Synonym: | increased susceptibility to immune complex mediated hypersensitivity |
| MP id: | MP:0005615 |
| Definition: | greater likelihood of developing tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via antibodies encountering circulating antigen; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury |
| Number of paths to term: | 5 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
immune system phenotypeabnormal immune system physiologyabnormal adaptive immunityabnormal type III hypersensitivity reactiondecreased susceptibility to type III hypersensitivity reactionincreased susceptibility to type III hypersensitivity reaction [MP:0005615] (10 genotypes, 10 annotations)immune system phenotypeabnormal immune system physiologyabnormal hypersensitivity reactionabnormal type III hypersensitivity reactiondecreased susceptibility to type III hypersensitivity reactionincreased susceptibility to type III hypersensitivity reaction [MP:0005615] (10 genotypes, 10 annotations)immune system phenotypeabnormal immune system physiologyabnormal inflammatory responseabnormal acute inflammationabnormal type III hypersensitivity reactiondecreased susceptibility to type III hypersensitivity reactionincreased susceptibility to type III hypersensitivity reaction [MP:0005615] (10 genotypes, 10 annotations)immune system phenotypeabnormal immune system physiologyabnormal inflammatory responseabnormal acute inflammationincreased acute inflammationincreased susceptibility to endotoxin shockincreased susceptibility to type I hypersensitivity reactionincreased susceptibility to type II hypersensitivity reactionincreased susceptibility to type III hypersensitivity reaction [MP:0005615] (10 genotypes, 10 annotations)increased susceptibility to type IV hypersensitivity reactionimmune system phenotypeabnormal immune system physiologyabnormal inflammatory responseincreased inflammatory responseincreased acute inflammationincreased susceptibility to endotoxin shockincreased susceptibility to type I hypersensitivity reactionincreased susceptibility to type II hypersensitivity reactionincreased susceptibility to type III hypersensitivity reaction [MP:0005615] (10 genotypes, 10 annotations)increased susceptibility to type IV hypersensitivity reactionMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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