About   Help   FAQ
Mammalian Phenotype Browser
Term Detail
MP term:increased susceptibility to type I hypersensitivity reaction
Synonym: decreased resistance to anaphylaxis
Synonym: decreased resistance to immediate type hypersensitivity
Synonym: decreased resistance to type I hypersensitivity reaction
Synonym: increased susceptibility to allergic response
Synonym: increased susceptibility to anaphylaxis
Synonym: increased susceptibility to immediate type hypersensitivity
MP id: MP:0005596
Alternate id: MP:0001878
Definition: greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal type I hypersensitivity reaction
                                        is-adecreased susceptibility to type I hypersensitivity reaction
                                        is-aincreased susceptibility to type I hypersensitivity reaction [MP:0005596] (47 genotypes, 47 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal hypersensitivity reaction
                                is-aabnormal type I hypersensitivity reaction
                                        is-adecreased susceptibility to type I hypersensitivity reaction
                                        is-aincreased susceptibility to type I hypersensitivity reaction [MP:0005596] (47 genotypes, 47 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal inflammatory response
                                is-aabnormal acute inflammation
                                        is-aabnormal type I hypersensitivity reaction
                                                is-adecreased susceptibility to type I hypersensitivity reaction
                                                is-aincreased susceptibility to type I hypersensitivity reaction [MP:0005596] (47 genotypes, 47 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal inflammatory response
                                is-aabnormal acute inflammation
                                        is-aincreased acute inflammation
                                                is-aincreased susceptibility to endotoxin shock
                                                is-aincreased susceptibility to type I hypersensitivity reaction [MP:0005596] (47 genotypes, 47 annotations)
                                                is-aincreased susceptibility to type II hypersensitivity reaction
                                                is-aincreased susceptibility to type III hypersensitivity reaction
                                                is-aincreased susceptibility to type IV hypersensitivity reaction


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal inflammatory response
                                is-aincreased inflammatory response
                                        is-aincreased acute inflammation
                                                is-aincreased susceptibility to endotoxin shock
                                                is-aincreased susceptibility to type I hypersensitivity reaction [MP:0005596] (47 genotypes, 47 annotations)
                                                is-aincreased susceptibility to type II hypersensitivity reaction
                                                is-aincreased susceptibility to type III hypersensitivity reaction
                                                is-aincreased susceptibility to type IV hypersensitivity reaction

Back to entry page

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory