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Mammalian Phenotype Browser
Term Detail
MP term:abnormal mast cell differentiation
MP id: MP:0005462
Definition: atypical production of or inability to produce a cell that is found in almost all tissues, containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell differentiation
                                is-aabnormal granulocyte differentiation
                                        is-aabnormal eosinophil differentiation
                                        is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                        is-aabnormal neutrophil differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal granulocyte morphology
                                                                is-aabnormal granulocyte differentiation
                                                                        is-aabnormal eosinophil differentiation
                                                                        is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                                        is-aabnormal neutrophil differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal granulocyte morphology
                                                                is-aabnormal mast cell morphology
                                                                        is-aabnormal dermal mast cell morphology
                                                                        is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                                        is-aabnormal mast cell number +
                                                                        is-adecreased mast cell histamine storage
                                                                        is-adecreased mast cell protease storage


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukopoiesis
                                                is-aabnormal myelopoiesis
                                                        is-aabnormal granulocyte differentiation
                                                                is-aabnormal eosinophil differentiation
                                                                is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                                is-aabnormal neutrophil differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukopoiesis
                                                is-aabnormal myelopoiesis
                                                        is-aabnormal granulocyte differentiation +
                                                        is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                        is-aabnormal monocyte differentiation
                                                        is-afailure of myelopoiesis
                                                        is-aimpaired myelopoiesis
                                                        is-amyeloid hyperplasia


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal granulocyte morphology
                                                        is-aabnormal granulocyte differentiation
                                                                is-aabnormal eosinophil differentiation
                                                                is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                                is-aabnormal neutrophil differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal granulocyte morphology
                                                        is-aabnormal mast cell morphology
                                                                is-aabnormal dermal mast cell morphology
                                                                is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                                is-aabnormal mast cell number +
                                                                is-adecreased mast cell histamine storage
                                                                is-adecreased mast cell protease storage


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukopoiesis
                                        is-aabnormal myelopoiesis
                                                is-aabnormal granulocyte differentiation
                                                        is-aabnormal eosinophil differentiation
                                                        is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                        is-aabnormal neutrophil differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukopoiesis
                                        is-aabnormal myelopoiesis
                                                is-aabnormal granulocyte differentiation +
                                                is-aabnormal mast cell differentiation [MP:0005462] (8 genotypes, 8 annotations)
                                                is-aabnormal monocyte differentiation
                                                is-afailure of myelopoiesis
                                                is-aimpaired myelopoiesis
                                                is-amyeloid hyperplasia

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory