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Mammalian Phenotype Browser
Term Detail
MP term:abnormal neurotransmitter secretion
Synonym: abnormal neurotransmitter release
Synonym: abnormal synaptic release
MP id: MP:0005445
Definition: anomaly in the production or release of endogenous signaling molecules into a synaptic cleft; neurotransmitters are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal synaptic transmission
                                is-aabnormal channel response +
                                is-aabnormal CNS synaptic transmission +
                                is-aabnormal neurotransmitter level
                                is-aabnormal neurotransmitter secretion [MP:0005445] (100 genotypes, 108 annotations)
                                        is-aabnormal synaptic acetylcholine release
                                        is-aabnormal synaptic dopamine release
                                        is-aabnormal synaptic epinephrine release
                                        is-aabnormal synaptic glutamate release +
                                        is-aabnormal synaptic norepinephrine release
                                        is-adecreased neurotransmitter release +
                                        is-aincreased neurotransmitter release
                                is-aabnormal neurotransmitter uptake
                                is-aabnormal paired-pulse facilitation +
                                is-aabnormal paired-pulse inhibition
                                is-aabnormal PNS synaptic transmission +

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.08
The Jackson Laboratory