| MP term: | abnormal pro-B cell morphology |
| Synonym: | abnormal B cell progenitor |
| Synonym: | abnormal progenitor B cell |
| Synonym: | pro-B cell abnormalities |
| MP id: | MP:0005432 |
| Definition: | any structural anomaly of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs |
| Number of paths to term: | 12 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationhematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal bone marrow cell morphology/developmentabnormal myeloblast morphology/developmentabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationimmune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology [MP:0005432] (174 genotypes, 187 annotations)abnormal early pro-B cell +abnormal late pro-B cell +abnormal pre-pro B cell morphology +abnormal pro-B cell differentiationdecreased pro-B cell number +increased pro-B cell number +abnormal somatic hypermutation frequencyarrested B cell differentiationMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
||
|
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support. |
last database update 05/08/2013 MGI 5.13 |
|
|
|
||
Analysis Tools