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Mammalian Phenotype Browser
Term Detail
MP term:abnormal cholesterol homeostasis
MP id: MP:0005278
Definition: anomaly in the processes involved in the maintenance of an internal equilibrium of cholesterol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal bile salt homeostasis +
                                is-aabnormal cholesterol homeostasis [MP:0005278] (1109 genotypes, 1806 annotations)
                                        is-aabnormal cholesterol level +
                                is-aabnormal circulating ketone body level +
                                is-aabnormal intestinal lipid absorption +
                                is-aabnormal lipid level +
                                is-aabnormal lipid oxidation +
                                is-aabnormal lipolysis +
                                is-adecreased susceptibility to hyperlipidemia
                                is-axanthoma

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory