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Mammalian Phenotype Browser
Term Detail
MP term:increased circulating cholesterol level
Synonym: elevated total circulating cholesterol level
Synonym: elevated total plasma cholesterol level
Synonym: elevated total serum cholesterol level
Synonym: high serum cholesterol level
Synonym: hypercholesterolemia
Synonym: increased total circulating cholesterol level
Synonym: increased total plasma cholesterol level
Synonym: increased total serum cholesterol level
MP id: MP:0005178
Alternate id: MP:0001550, MP:0002615
Definition: greater than the normal amount in the blood of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal blood homeostasis
                                is-aabnormal circulating lipid level
                                        is-aabnormal circulating cholesterol level
                                                is-aabnormal circulating HDL cholesterol level +
                                                is-aabnormal circulating non-HDL cholesterol level +
                                                is-adecreased circulating cholesterol level +
                                                is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                        is-aincreased circulating HDL cholesterol level
                                                        is-aincreased circulating LDL cholesterol level
                                                        is-aincreased circulating VLDL cholesterol level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal cholesterol homeostasis
                                        is-aabnormal cholesterol level
                                                is-aabnormal circulating cholesterol level
                                                        is-aabnormal circulating HDL cholesterol level +
                                                        is-aabnormal circulating non-HDL cholesterol level +
                                                        is-adecreased circulating cholesterol level +
                                                        is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                                is-aincreased circulating HDL cholesterol level
                                                                is-aincreased circulating LDL cholesterol level
                                                                is-aincreased circulating VLDL cholesterol level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal cholesterol homeostasis
                                        is-aabnormal cholesterol level
                                                is-aincreased cholesterol level
                                                        is-aincreased brain cholesterol level
                                                        is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                                is-aincreased circulating HDL cholesterol level
                                                                is-aincreased circulating LDL cholesterol level
                                                                is-aincreased circulating VLDL cholesterol level
                                                        is-aincreased liver cholesterol level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal lipid level
                                        is-aabnormal circulating lipid level
                                                is-aabnormal circulating cholesterol level
                                                        is-aabnormal circulating HDL cholesterol level +
                                                        is-aabnormal circulating non-HDL cholesterol level +
                                                        is-adecreased circulating cholesterol level +
                                                        is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                                is-aincreased circulating HDL cholesterol level
                                                                is-aincreased circulating LDL cholesterol level
                                                                is-aincreased circulating VLDL cholesterol level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal lipid level
                                        is-aabnormal sterol level
                                                is-aabnormal cholesterol level
                                                        is-aabnormal circulating cholesterol level
                                                                is-aabnormal circulating HDL cholesterol level +
                                                                is-aabnormal circulating non-HDL cholesterol level +
                                                                is-adecreased circulating cholesterol level +
                                                                is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                                        is-aincreased circulating HDL cholesterol level
                                                                        is-aincreased circulating LDL cholesterol level
                                                                        is-aincreased circulating VLDL cholesterol level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal lipid level
                                        is-aabnormal sterol level
                                                is-aabnormal cholesterol level
                                                        is-aincreased cholesterol level
                                                                is-aincreased brain cholesterol level
                                                                is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                                        is-aincreased circulating HDL cholesterol level
                                                                        is-aincreased circulating LDL cholesterol level
                                                                        is-aincreased circulating VLDL cholesterol level
                                                                is-aincreased liver cholesterol level


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal lipid homeostasis
                                is-aabnormal lipid level
                                        is-aabnormal sterol level
                                                is-aincreased sterol level
                                                        is-aincreased cholesterol level
                                                                is-aincreased brain cholesterol level
                                                                is-aincreased circulating cholesterol level [MP:0005178] (598 genotypes, 824 annotations)
                                                                        is-aincreased circulating HDL cholesterol level
                                                                        is-aincreased circulating LDL cholesterol level
                                                                        is-aincreased circulating VLDL cholesterol level
                                                                is-aincreased liver cholesterol level

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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory