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Mammalian Phenotype Browser
Term Detail
MP term:abnormal blood-brain barrier function
MP id: MP:0005167
Definition: anomaly in the function of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acardiovascular system phenotype
                is-aabnormal cardiovascular system physiology
                        is-aabnormal blood vessel physiology
                                is-aabnormal blood-brain barrier function [MP:0005167] (35 genotypes, 35 annotations)
                                is-aabnormal blood-cerebrospinal fluid barrier function
                                is-aabnormal blood-inner ear barrier function
                                is-aabnormal carotid body physiology
                                is-aabnormal vascular endothelial cell physiology
                                is-aabnormal vascular permeability +
                                is-aabnormal vascular smooth muscle physiology +
                                is-aabnormal vascular wound healing
                                is-apathological neovascularization +
                                is-aperivascular fibrosis
                                is-avascular inflammation +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal autonomic nervous system physiology +
                        is-aabnormal blood-brain barrier function [MP:0005167] (35 genotypes, 35 annotations)
                        is-aabnormal blood-cerebrospinal fluid barrier function
                        is-aabnormal central pattern generator function +
                        is-aabnormal cerebrospinal fluid production +
                        is-aabnormal dopamine level +
                        is-aabnormal embryonic neuroepithelial cell proliferation +
                        is-aabnormal endoneurial fluid pressure +
                        is-aabnormal ependyma motile cilium physiology +
                        is-aabnormal glial cell physiology +
                        is-aabnormal hippocampus physiology
                        is-aabnormal hypothalamus physiology +
                        is-aabnormal myelination +
                        is-aabnormal nervous system electrophysiology +
                        is-aabnormal nervous system regeneration +
                        is-aabnormal neuron physiology +
                        is-aabnormal neuronal stem cell physiology +
                        is-aabnormal pineal gland physiology +
                        is-aabnormal pituitary gland physiology +
                        is-aabnormal sensorimotor gating +
                        is-aabnormal somatic nervous system physiology +
                        is-aabnormal somatosensory cortex physiology +
                        is-aabnormal synaptic plasticity +
                        is-aabnormal synaptic transmission +
                        is-aaltered response to CNS ischemic injury +
                        is-aCNS inflammation +
                        is-aCNS ischemia
                        is-adecreased hindbrain apoptosis
                        is-aendoneurial edema
                        is-aincreased forebrain apoptosis
                        is-aincreased hindbrain apoptosis
                        is-aincreased midbrain apoptosis
                        is-aincreased neural tube apoptosis +
                        is-aincreased spinal cord apoptosis
                        is-aintracranial hemorrhage +
                        is-aseizures +
                        is-aspinal hemorrhage

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory