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Mammalian Phenotype Browser
Term Detail
MP term:abnormal osteoclast morphology
Synonym: abnormal chondroclast morphology
Synonym: abnormal osteophage morphology
MP id: MP:0004982
Definition: any structural anomaly of the specialized phagocytic cells associated with the absorption and removal of the mineralized matrix of bone tissue
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology
                                                                        is-aabnormal alveolar macrophage morphology
                                                                        is-aabnormal Kupffer cell morphology
                                                                        is-aabnormal macrophage derived foam cell morphology +
                                                                        is-aabnormal macrophage differentiation
                                                                        is-aabnormal metallophilic macrophage morphology
                                                                        is-aabnormal microglial cell morphology +
                                                                        is-aabnormal osteoclast morphology [MP:0004982] (252 genotypes, 347 annotations)
                                                                                is-aabnormal osteoclast cell number +
                                                                                is-aabnormal osteoclast differentiation
                                                                        is-aabnormal peritoneal macrophage morphology
                                                                        is-aabnormal perivascular macrophage morphology
                                                                        is-aabnormal spleen marginal zone macrophage morphology
                                                                        is-adecreased macrophage cell number +
                                                                        is-aincreased macrophage cell number +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal phagocyte morphology
                                                                is-aabnormal mononuclear phagocyte morphology
                                                                        is-aabnormal macrophage morphology
                                                                                is-aabnormal alveolar macrophage morphology
                                                                                is-aabnormal Kupffer cell morphology
                                                                                is-aabnormal macrophage derived foam cell morphology +
                                                                                is-aabnormal macrophage differentiation
                                                                                is-aabnormal metallophilic macrophage morphology
                                                                                is-aabnormal microglial cell morphology +
                                                                                is-aabnormal osteoclast morphology [MP:0004982] (252 genotypes, 347 annotations)
                                                                                        is-aabnormal osteoclast cell number +
                                                                                        is-aabnormal osteoclast differentiation
                                                                                is-aabnormal peritoneal macrophage morphology
                                                                                is-aabnormal perivascular macrophage morphology
                                                                                is-aabnormal spleen marginal zone macrophage morphology
                                                                                is-adecreased macrophage cell number +
                                                                                is-aincreased macrophage cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal mononuclear phagocyte morphology
                                                        is-aabnormal macrophage morphology
                                                                is-aabnormal alveolar macrophage morphology
                                                                is-aabnormal Kupffer cell morphology
                                                                is-aabnormal macrophage derived foam cell morphology +
                                                                is-aabnormal macrophage differentiation
                                                                is-aabnormal metallophilic macrophage morphology
                                                                is-aabnormal microglial cell morphology +
                                                                is-aabnormal osteoclast morphology [MP:0004982] (252 genotypes, 347 annotations)
                                                                        is-aabnormal osteoclast cell number +
                                                                        is-aabnormal osteoclast differentiation
                                                                is-aabnormal peritoneal macrophage morphology
                                                                is-aabnormal perivascular macrophage morphology
                                                                is-aabnormal spleen marginal zone macrophage morphology
                                                                is-adecreased macrophage cell number +
                                                                is-aincreased macrophage cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal phagocyte morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology
                                                                        is-aabnormal alveolar macrophage morphology
                                                                        is-aabnormal Kupffer cell morphology
                                                                        is-aabnormal macrophage derived foam cell morphology +
                                                                        is-aabnormal macrophage differentiation
                                                                        is-aabnormal metallophilic macrophage morphology
                                                                        is-aabnormal microglial cell morphology +
                                                                        is-aabnormal osteoclast morphology [MP:0004982] (252 genotypes, 347 annotations)
                                                                                is-aabnormal osteoclast cell number +
                                                                                is-aabnormal osteoclast differentiation
                                                                        is-aabnormal peritoneal macrophage morphology
                                                                        is-aabnormal perivascular macrophage morphology
                                                                        is-aabnormal spleen marginal zone macrophage morphology
                                                                        is-adecreased macrophage cell number +
                                                                        is-aincreased macrophage cell number +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal macrophage morphology
                                                is-aabnormal alveolar macrophage morphology
                                                is-aabnormal Kupffer cell morphology
                                                is-aabnormal macrophage derived foam cell morphology +
                                                is-aabnormal macrophage differentiation
                                                is-aabnormal metallophilic macrophage morphology
                                                is-aabnormal microglial cell morphology +
                                                is-aabnormal osteoclast morphology [MP:0004982] (252 genotypes, 347 annotations)
                                                        is-aabnormal osteoclast cell number +
                                                        is-aabnormal osteoclast differentiation
                                                is-aabnormal peritoneal macrophage morphology
                                                is-aabnormal perivascular macrophage morphology
                                                is-aabnormal spleen marginal zone macrophage morphology
                                                is-adecreased macrophage cell number +
                                                is-aincreased macrophage cell number +


mammalian phenotype
        is-askeleton phenotype
                is-aabnormal skeleton morphology
                        is-aabnormal bone structure
                                is-aabnormal bone collagen fibril morphology
                                is-aabnormal bone marrow cavity morphology
                                is-aabnormal bone marrow morphology +
                                is-aabnormal bone mineral content +
                                is-aabnormal bone mineral density +
                                is-aabnormal bone volume +
                                is-aabnormal compact bone morphology +
                                is-aabnormal osteoblast morphology +
                                is-aabnormal osteoclast morphology [MP:0004982] (252 genotypes, 347 annotations)
                                        is-aabnormal osteoclast cell number +
                                        is-aabnormal osteoclast differentiation
                                is-aabnormal periosteum morphology +
                                is-aabnormal trabecular bone morphology +
                                is-aaltered susceptibility to osteoporosis +
                                is-adecreased bone mass +
                                is-aexostosis
                                is-aincreased bone mass +
                                is-aosteosclerosis

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory