| MP term: | increased regulatory T cell number |
| Synonym: | increased suppressor T cell number |
| Synonym: | increased Treg cell number |
| MP id: | MP:0004973 |
| Definition: | greater number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity |
| Number of paths to term: | 35 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal hematopoietic cell numberabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal hematopoietic cell numberabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal hematopoietic cell numberabnormal leukocyte cell numberabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal hematopoietic cell numberabnormal leukocyte cell numberincreased leukocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal hematopoietic cell numberincreased hematopoietic cell numberincreased leukocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal leukocyte cell numberincreased leukocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal regulatory T cell morphologyabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal leukocyte cell numberincreased leukocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal regulatory T cell morphologyabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal leukocyte cell numberabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal leukocyte cell numberincreased leukocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphocyte cell numberincreased lymphocyte cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal regulatory T cell morphologyabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal T cell numberabnormal regulatory T cell numberdecreased regulatory T cell number +increased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal T cell numberincreased T cell numberincreased activated T cell numberincreased double-negative T cell number +increased double-positive T cell numberincreased gamma-delta T cell number +increased memory T cell number +increased NK T cell numberincreased regulatory T cell number [MP:0004973] (38 genotypes, 38 annotations)increased single-positive T cell number +increased thymocyte number +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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