| MP term: | abnormal regulatory T cell morphology |
| Synonym: | abnormal regulatory T-cell morphology |
| Synonym: | abnormal regulatory T-lymphocyte |
| Synonym: | abnormal regulatory T lymphocyte morphology |
| Synonym: | abnormal suppressor T cell morphology |
| Synonym: | abnormal suppressor T-cell morphology |
| Synonym: | abnormal suppressor T cell morphology/development |
| Synonym: | abnormal suppressor T lymphocyte morphology |
| Synonym: | abnormal suppressor T-lymphocyte morphology |
| Synonym: | abnormal Treg cell morphology |
| Synonym: | suppressor T cell abnormalities |
| Synonym: | suppressor T-cell abnormalities |
| MP id: | MP:0004941 |
| Alternate id: | MP:0002437 |
| Definition: | any structural anomaly of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or Tregs) and other T cell types that have suppressor function |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal effector T cell morphology +abnormal gamma-delta T cell morphology +abnormal intraepithelial T cell morphology +abnormal memory T cell morphology +abnormal NK T cell morphology +abnormal regulatory T cell morphology [MP:0004941] (114 genotypes, 126 annotations)abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology +abnormal CD8-positive, alpha-beta regulatory T cell morphologyabnormal regulatory T cell number +abnormal T cell differentiation +abnormal T cell number +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal effector T cell morphology +abnormal gamma-delta T cell morphology +abnormal intraepithelial T cell morphology +abnormal memory T cell morphology +abnormal NK T cell morphology +abnormal regulatory T cell morphology [MP:0004941] (114 genotypes, 126 annotations)abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology +abnormal CD8-positive, alpha-beta regulatory T cell morphologyabnormal regulatory T cell number +abnormal T cell differentiation +abnormal T cell number +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal T cell morphologyabnormal effector T cell morphology +abnormal gamma-delta T cell morphology +abnormal intraepithelial T cell morphology +abnormal memory T cell morphology +abnormal NK T cell morphology +abnormal regulatory T cell morphology [MP:0004941] (114 genotypes, 126 annotations)abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology +abnormal CD8-positive, alpha-beta regulatory T cell morphologyabnormal regulatory T cell number +abnormal T cell differentiation +abnormal T cell number +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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