MGI 5.13 - Phenotype Browser

Mammalian Phenotype Browser
Term Detail

MP term:	abnormal paired-pulse inhibition
Synonym:	abnormal paired pulse depression
Synonym:	abnormal paired pulse inhibition
Synonym:	abnormal PPI
MP id:	MP:0004807
Definition:	defects in the suppressive response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of inhibition of neurotransmitter release at the second stimulus
Number of paths to term:	1

denotes an 'is-a' relationship
denotes a 'part-of' relationship

mammalian phenotype

nervous system phenotype

abnormal nervous system physiology

abnormal synaptic transmission

abnormal channel response +

abnormal CNS synaptic transmission +

abnormal neurotransmitter level +

abnormal paired-pulse facilitation +

abnormal paired-pulse inhibition [MP:0004807] (12 genotypes, 12 annotations)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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