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Mammalian Phenotype Browser
Term Detail
MP term:abnormal paired-pulse inhibition
Synonym: abnormal paired pulse depression
Synonym: abnormal paired pulse inhibition
Synonym: abnormal PPI
MP id: MP:0004807
Definition: defects in the suppressive response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of inhibition of neurotransmitter release at the second stimulus
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal synaptic transmission
                                is-aabnormal channel response +
                                is-aabnormal CNS synaptic transmission +
                                is-aabnormal neurotransmitter level +
                                is-aabnormal paired-pulse facilitation +
                                is-aabnormal paired-pulse inhibition [MP:0004807] (13 genotypes, 13 annotations)
                                is-aabnormal PNS synaptic transmission +

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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory