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Mammalian Phenotype Browser
Term Detail
MP term:impaired acrosome reaction
MP id: MP:0004542
Definition: reduced ability or inability to execute the cellular exocytosis of a single, anterior secretory granule following a sperm's attachment to the zona pellucida surrounding an oocyte
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal vesicle-mediated transport
                                is-aabnormal acrosome reaction
                                        is-aimpaired acrosome reaction [MP:0004542] (34 genotypes, 34 annotations)
                                        is-apremature acrosome reaction


mammalian phenotype
        is-areproductive system phenotype
                is-aabnormal reproductive system physiology
                        is-aabnormal fertilization
                                is-adecreased fertilization frequency
                                is-adelayed fertilization
                                is-aimpaired acrosome reaction [MP:0004542] (34 genotypes, 34 annotations)
                                is-aimpaired fertilization


mammalian phenotype
        is-areproductive system phenotype
                is-aabnormal reproductive system physiology
                        is-aabnormal male reproductive system physiology
                                is-aabnormal sperm physiology
                                        is-aabnormal acrosome reaction
                                                is-aimpaired acrosome reaction [MP:0004542] (34 genotypes, 34 annotations)
                                                is-apremature acrosome reaction

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory