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Mammalian Phenotype Browser
Term Detail
MP term:abnormal cochlear outer hair cell physiology
Synonym: abnormal cochlear OHC physiology
MP id: MP:0004434
Definition: any functional anomaly in processes pertinent to the function of cochlear OHCs which are known to enhance the performance of the cochlea, both qualitatively (increased selectivity) and quantitatively (increased sensitivity); in addition to the mechanoelectric transduction required for auditory sensation, OHCs also perform electromechanical transduction, whereby transmembrane voltage drives rapid changes in the length and stiffness of OHCs at audio frequencies in vitro (electromotility)
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahearing/vestibular/ear phenotype
                is-aabnormal ear physiology
                        is-aabnormal hair cell physiology
                                is-aabnormal cochlear hair cell physiology
                                        is-aabnormal cochlear inner hair cell physiology
                                        is-aabnormal cochlear outer hair cell physiology [MP:0004434] (32 genotypes, 40 annotations)
                                                is-aabnormal cochlear microphonics +
                                                is-aabnormal cochlear outer hair cell electromotility +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal neuron physiology
                                is-aabnormal sensory neuron physiology
                                        is-aabnormal hair cell physiology
                                                is-aabnormal cochlear hair cell physiology
                                                        is-aabnormal cochlear inner hair cell physiology
                                                        is-aabnormal cochlear outer hair cell physiology [MP:0004434] (32 genotypes, 40 annotations)
                                                                is-aabnormal cochlear microphonics +
                                                                is-aabnormal cochlear outer hair cell electromotility +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal somatic nervous system physiology
                                is-aabnormal sensory neuron physiology
                                        is-aabnormal hair cell physiology
                                                is-aabnormal cochlear hair cell physiology
                                                        is-aabnormal cochlear inner hair cell physiology
                                                        is-aabnormal cochlear outer hair cell physiology [MP:0004434] (32 genotypes, 40 annotations)
                                                                is-aabnormal cochlear microphonics +
                                                                is-aabnormal cochlear outer hair cell electromotility +

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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory