| MP term: | abnormal cochlear outer hair cell physiology |
| Synonym: | abnormal cochlear OHC physiology |
| MP id: | MP:0004434 |
| Definition: | any functional anomaly in processes pertinent to the function of cochlear OHCs which are known to enhance the performance of the cochlea, both qualitatively (increased selectivity) and quantitatively (increased sensitivity); in addition to the mechanoelectric transduction required for auditory sensation, OHCs also perform electromechanical transduction, whereby transmembrane voltage drives rapid changes in the length and stiffness of OHCs at audio frequencies in vitro (electromotility) |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
hearing/vestibular/ear phenotypeabnormal ear physiologyabnormal hair cell physiologyabnormal cochlear hair cell physiologyabnormal cochlear inner hair cell physiologyabnormal cochlear outer hair cell physiology [MP:0004434] (32 genotypes, 40 annotations)abnormal cochlear microphonics +abnormal cochlear outer hair cell electromotility +nervous system phenotypeabnormal nervous system physiologyabnormal neuron physiologyabnormal sensory neuron physiologyabnormal hair cell physiologyabnormal cochlear hair cell physiologyabnormal cochlear inner hair cell physiologyabnormal cochlear outer hair cell physiology [MP:0004434] (32 genotypes, 40 annotations)abnormal cochlear microphonics +abnormal cochlear outer hair cell electromotility +nervous system phenotypeabnormal nervous system physiologyabnormal somatic nervous system physiologyabnormal sensory neuron physiologyabnormal hair cell physiologyabnormal cochlear hair cell physiologyabnormal cochlear inner hair cell physiologyabnormal cochlear outer hair cell physiology [MP:0004434] (32 genotypes, 40 annotations)abnormal cochlear microphonics +abnormal cochlear outer hair cell electromotility +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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