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Mammalian Phenotype Browser
Term Detail
MP term:tau protein deposits
Synonym: tau protein tangles
MP id: MP:0004250
Definition: formation of self-assembled tangles of paired helical filaments and straight filaments due to hyperphosphorylation of the tau protein; often seen in neuronal tissues of individuals with neurodegenerative disorders
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal brain cholesterol level +
                                is-aabnormal brain copper level +
                                is-aabnormal brain development +
                                is-aabnormal brain interneuron morphology
                                is-aabnormal brain iron level
                                is-aabnormal brain size +
                                is-aabnormal brain vasculature morphology +
                                is-aabnormal brain ventricular system morphology +
                                is-aabnormal brain white matter morphology +
                                is-aabnormal brainstem morphology +
                                is-aabnormal forebrain morphology +
                                is-aabnormal hindbrain morphology +
                                is-aabnormal midbrain morphology +
                                is-aabnormal postnatal subventricular zone morphology +
                                is-abrain atrophy +
                                is-abrain vacuoles
                                is-acerebral amyloid angiopathy
                                is-adecreased brain plasmalogen level
                                is-aincreased brain plasmalogen level
                                is-aneurofibrillary tangles
                                is-atau protein deposits [MP:0004250] (47 genotypes, 47 annotations)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory