About   Help   FAQ
Mammalian Phenotype Browser
Term Detail
MP term:tau protein deposits
Synonym: tau protein tangles
MP id: MP:0004250
Definition: formation of self-assembled tangles of paired helical filaments and straight filaments due to hyperphosphorylation of the tau protein; often seen in neuronal tissues of individuals with neurodegenerative disorders
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal brain cholesterol level +
                                is-aabnormal brain copper level +
                                is-aabnormal brain development +
                                is-aabnormal brain interneuron morphology
                                is-aabnormal brain iron level +
                                is-aabnormal brain size +
                                is-aabnormal brain vasculature morphology +
                                is-aabnormal brain ventricular system morphology +
                                is-aabnormal brain white matter morphology +
                                is-aabnormal brainstem morphology +
                                is-aabnormal circumventricular organ morphology +
                                is-aabnormal forebrain morphology +
                                is-aabnormal hindbrain morphology +
                                is-aabnormal midbrain morphology +
                                is-aabnormal postnatal subventricular zone morphology +
                                is-abasal brain tissue herniation
                                is-abrain atrophy +
                                is-abrain vacuoles
                                is-adecreased brain plasmalogen level
                                is-adecreased sulfoglycosphingolipid level +
                                is-aincreased brain plasmalogen level
                                is-aincreased brain sulfoglycosphingolipid level
                                is-aneurofibrillary tangles
                                is-atau protein deposits [MP:0004250] (57 genotypes, 57 annotations)

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-anervous system inclusion bodies
                                is-aalpha-synuclein inclusion body
                                is-aamyloid beta deposits
                                is-aargyrophilic inclusion bodies
                                is-acerebral amyloid angiopathy
                                is-aHirano bodies
                                is-aLafora bodies
                                is-aLewy bodies
                                is-aneurofibrillary tangles
                                is-aRosenthal fibers
                                is-atau protein deposits [MP:0004250] (57 genotypes, 57 annotations)

Back to entry page

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.08
The Jackson Laboratory