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Mammalian Phenotype Browser
Term Detail
MP term:abnormal midbrain-hindbrain boundary development
Synonym: abnormal isthmic organizer development
Synonym: abnormal isthmomesencephalic boundary development
Synonym: abnormal isthmus development
Synonym: abnormal isthmus organizer development
Synonym: abnormal MHB development
Synonym: abnormal midbrain-hindbrain organizer development
MP id: MP:0004096
Definition: anomaly in the formation of the midbrain-hindbrain domain, comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; an organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal brain development
                                        is-aabnormal midbrain-hindbrain boundary morphology
                                                is-aabnormal midbrain-hindbrain boundary development [MP:0004096] (11 genotypes, 11 annotations)
                                                is-aabsent midbrain-hindbrain boundary


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal nervous system development
                                is-aabnormal brain development
                                        is-aabnormal midbrain-hindbrain boundary morphology
                                                is-aabnormal midbrain-hindbrain boundary development [MP:0004096] (11 genotypes, 11 annotations)
                                                is-aabsent midbrain-hindbrain boundary

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory