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Mammalian Phenotype Browser
Term Detail
MP term:abnormal neural tube closure
Synonym: abnormal neural fold fusion
Synonym: abnormal neural tube fusion
MP id: MP:0003720
Definition: any anomaly in the last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal embryonic tissue morphology
                                is-aabnormal neural tube morphology/development
                                        is-aabnormal embryonic neuroepithelium morphology +
                                        is-aabnormal floor plate morphology +
                                        is-aabnormal lamina terminalis morphology +
                                        is-aabnormal neural crest morphology +
                                        is-aabnormal neural tube closure [MP:0003720] (569 genotypes, 664 annotations)
                                                is-adelayed neural tube closure +
                                                is-aincomplete caudal neuropore closure
                                                is-aincomplete rostral neuropore closure
                                                is-aopen neural tube +
                                        is-aabnormal neural tube mantle layer morphology +
                                        is-aabnormal neural tube marginal layer morphology
                                        is-aabnormal neural tube ventricular layer morphology
                                        is-aabnormal neuromere morphology +
                                        is-aabnormal neuropore morphology +
                                        is-aabnormal roof plate morphology +
                                        is-acaudal rachischisis
                                        is-acraniorachischisis
                                        is-akinked neural tube
                                        is-aneural tube degeneration
                                        is-awavy neural tube


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal nervous system development
                                is-aabnormal neural tube morphology/development
                                        is-aabnormal embryonic neuroepithelium morphology +
                                        is-aabnormal floor plate morphology +
                                        is-aabnormal lamina terminalis morphology +
                                        is-aabnormal neural crest morphology +
                                        is-aabnormal neural tube closure [MP:0003720] (569 genotypes, 664 annotations)
                                                is-adelayed neural tube closure +
                                                is-aincomplete caudal neuropore closure
                                                is-aincomplete rostral neuropore closure
                                                is-aopen neural tube +
                                        is-aabnormal neural tube mantle layer morphology +
                                        is-aabnormal neural tube marginal layer morphology
                                        is-aabnormal neural tube ventricular layer morphology
                                        is-aabnormal neuromere morphology +
                                        is-aabnormal neuropore morphology +
                                        is-aabnormal roof plate morphology +
                                        is-acaudal rachischisis
                                        is-acraniorachischisis
                                        is-akinked neural tube
                                        is-aneural tube degeneration
                                        is-awavy neural tube

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory