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Mammalian Phenotype Browser
Term Detail
MP term:oxidative stress
Synonym: increased reactive oxygen species production
Synonym: increased ROS production
MP id: MP:0003674
Definition: condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal redox activity
                                is-aoxidative stress [MP:0003674] (187 genotypes, 187 annotations)

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MGI 6.08
The Jackson Laboratory