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Mammalian Phenotype Browser
Term Detail
MP term:abnormal leukocyte tethering or rolling
Synonym: abnormal leukocyte tethering
Synonym: abnormal lymphocyte rolling
MP id: MP:0003627
Definition: anomaly in the transient adhesive interactions between leukocytes and endothelial cells lining blood vessels mediated primarily by selectins and which are typically the first step in cellular extravasation
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell migration
                                is-aabnormal leukocyte migration
                                        is-aabnormal cellular extravasation
                                                is-aabnormal leukocyte tethering or rolling [MP:0003627] (66 genotypes, 66 annotations)


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal leukocyte migration
                                                is-aabnormal cellular extravasation
                                                        is-aabnormal leukocyte tethering or rolling [MP:0003627] (66 genotypes, 66 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal leukocyte migration
                                                is-aabnormal cellular extravasation
                                                        is-aabnormal leukocyte tethering or rolling [MP:0003627] (66 genotypes, 66 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal leukocyte migration
                                                is-aabnormal cellular extravasation
                                                        is-aabnormal leukocyte tethering or rolling [MP:0003627] (66 genotypes, 66 annotations)


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal leukocyte migration
                                                is-aabnormal cellular extravasation
                                                        is-aabnormal leukocyte tethering or rolling [MP:0003627] (66 genotypes, 66 annotations)

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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory