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Mammalian Phenotype Browser
Term Detail
MP term:kidney failure
Synonym: renal failure
Synonym: renal insufficiency
MP id: MP:0003606
Definition: failure of the kidneys to adequately filter toxins and waste products from the blood; classified as acute (as in acute kidney injury) or chronic (as in chronic kidney disease); a number of other diseases or health problems may cause either form of renal failure to occur
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system physiology
                        is-aabnormal kidney physiology
                                is-aabnormal kidney apoptosis +
                                is-aabnormal kidney cell proliferation +
                                is-aabnormal kidney epithelial cell primary cilium physiology
                                is-aabnormal kidney glutathione peroxidase activity +
                                is-aabnormal podocyte physiology +
                                is-aabnormal renal filtration +
                                is-aabnormal renal plasma flow rate +
                                is-aabnormal renal reabsorbtion +
                                is-aabnormal renal sympathetic nerve activity +
                                is-aabnormal renal transport +
                                is-aabnormal renal vascular resistance +
                                is-aabnormal renal water homeostasis +
                                is-aabnormal tubuloglomerular feedback response +
                                is-aaltered susceptibility to kidney reperfusion injury +
                                is-akidney failure [MP:0003606] (97 genotypes, 97 annotations)
                                is-akidney hemorrhage +
                                is-akidney inflammation +
                                is-arenal ischemia
                                is-arenal tubular acidosis
                                is-avesicoureteral reflux

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MGI 6.08
The Jackson Laboratory