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Mammalian Phenotype Browser
Term Detail
MP term:altered response to CNS ischemic injury
Synonym: response to stroke
MP id: MP:0003075
Definition: altered response to lack of adequate blood flow, due to trauma or disease, to support the normal functioning of a tissue in the central nervous system
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal response to injury
                        is-aabnormal Wallerian degeneration +
                        is-aabnormal wound healing +
                        is-aaltered response of heart to induced stress +
                        is-aaltered response to CNS ischemic injury [MP:0003075] (107 genotypes, 150 annotations)
                                is-adecreased susceptibility to ischemic brain injury +
                                is-aincreased susceptibility to ischemic brain injury +
                        is-aaltered response to myocardial infarction +
                        is-aaltered response to retinal ischemic injury +
                        is-aaltered susceptibility to kidney reperfusion injury +
                        is-adecreased susceptibility to injury +
                        is-aincreased susceptibility to injury +


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal autonomic nervous system physiology +
                        is-aabnormal blood-brain barrier function
                        is-aabnormal blood-cerebrospinal fluid barrier function
                        is-aabnormal central pattern generator function +
                        is-aabnormal cerebrospinal fluid production +
                        is-aabnormal dopamine level +
                        is-aabnormal embryonic neuroepithelial cell proliferation +
                        is-aabnormal endoneurial fluid pressure +
                        is-aabnormal ependyma motile cilium physiology +
                        is-aabnormal glial cell physiology +
                        is-aabnormal hippocampus physiology
                        is-aabnormal hypothalamus physiology +
                        is-aabnormal myelination +
                        is-aabnormal nervous system electrophysiology +
                        is-aabnormal nervous system regeneration +
                        is-aabnormal neuron physiology +
                        is-aabnormal neuronal stem cell physiology +
                        is-aabnormal pineal gland physiology +
                        is-aabnormal pituitary gland physiology +
                        is-aabnormal sensorimotor gating +
                        is-aabnormal somatic nervous system physiology +
                        is-aabnormal somatosensory cortex physiology +
                        is-aabnormal synaptic plasticity +
                        is-aabnormal synaptic transmission +
                        is-aaltered response to CNS ischemic injury [MP:0003075] (107 genotypes, 150 annotations)
                                is-adecreased susceptibility to ischemic brain injury +
                                is-aincreased susceptibility to ischemic brain injury +
                        is-aCNS inflammation +
                        is-aCNS ischemia
                        is-adecreased hindbrain apoptosis
                        is-aendoneurial edema
                        is-aincreased forebrain apoptosis
                        is-aincreased hindbrain apoptosis
                        is-aincreased midbrain apoptosis
                        is-aincreased neural tube apoptosis +
                        is-aincreased spinal cord apoptosis
                        is-aintracranial hemorrhage +
                        is-aseizures +
                        is-aspinal hemorrhage

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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory