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Mammalian Phenotype Browser
Term Detail
MP term:abnormal cardiac muscle contractility
Synonym: abnormal fractional shortening (FS)
Synonym: abnormal peak of aortic outflow velocity (PAV)
Synonym: abnormal velocity of circumferential fiber shortening (Vcfc)
Synonym: abnormal ventricular ejection fraction volume
MP id: MP:0002972
Definition: altered ability of the heart muscle to shorten or to develop increased tension, often measured by dP/dT max, fractional shortening (FS), velocity of circumferential fiber shortening (Vcfc), peak of aortic outflow velocity (PAV), and ventricular ejection fraction volume
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acardiovascular system phenotype
                is-aabnormal cardiovascular system physiology
                        is-aabnormal blood circulation +
                        is-aabnormal blood pressure regulation +
                        is-aabnormal blood vessel physiology +
                        is-aabnormal cardiac cell glucose uptake
                        is-aabnormal cardiac muscle contractility [MP:0002972] (454 genotypes, 494 annotations)
                                is-adecreased cardiac muscle contractility +
                                is-aincreased cardiac muscle contractility +
                        is-aabnormal cardiac muscle relaxation
                        is-aabnormal cardiac valve physiology +
                        is-aabnormal fetal cardiomyocyte physiology +
                        is-aabnormal heart echocardiography feature
                        is-aabnormal heart ventricle pressure +
                        is-aabnormal heartbeat +
                        is-aabnormal impulse conducting system conduction +
                        is-aabnormal mean heart rate adaptation +
                        is-aabnormal myocardial fiber physiology +
                        is-aabnormal pulmonary pressure +
                        is-aabnormal susceptibility to aortic cartilaginous metaplasia +
                        is-aabnormal susceptibility to diet-induced aortic fatty streak lesions +
                        is-aabnormal systemic arterial blood pressure +
                        is-aaltered response of heart to induced stress +
                        is-aaltered response to myocardial infarction +
                        is-acardiomyopathy +
                        is-acongestive heart failure
                        is-aheart inflammation +
                        is-aportal hypertension


mammalian phenotype
        is-amuscle phenotype
                is-aabnormal muscle physiology
                        is-aabnormal muscle contractility
                                is-aabnormal cardiac muscle contractility [MP:0002972] (454 genotypes, 494 annotations)
                                        is-adecreased cardiac muscle contractility +
                                        is-aincreased cardiac muscle contractility +
                                is-aabnormal vasoconstriction +
                                is-aimpaired muscle contractility +

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory