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Mammalian Phenotype Browser
Term Detail
MP term:impaired skin barrier function
MP id: MP:0002796
Definition: impaired ability of the skin to regulate water loss; frequently leads to dehydration
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal fluid regulation
                                is-aabnormal amniotic fluid composition
                                is-aabnormal renal water reabsorbtion
                                is-aascites +
                                is-adecreased salivation +
                                is-aedema +
                                is-ahydropic allantois
                                is-aimpaired skin barrier function [MP:0002796] (123 genotypes, 123 annotations)
                                is-aincreased salivation
                                is-apericardial effusion +
                                is-apleural effusion +

mammalian phenotype
        is-aintegument phenotype
                is-aabnormal skin physiology
                        is-aabnormal epidermal stem cell physiology +
                        is-aabnormal keratinocyte physiology +
                        is-aabnormal pruritus +
                        is-aabnormal sebocyte physiology +
                        is-aabnormal skin exfoliation
                        is-aabnormal skin tensile strength +
                        is-adecreased sensitivity to skin irradiation
                        is-aimpaired skin barrier function [MP:0002796] (123 genotypes, 123 annotations)
                        is-aincreased sensitivity to skin irradiation
                        is-askin inflammation +
                        is-askin photosensitivity

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MGI 6.08
The Jackson Laboratory