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Mammalian Phenotype Browser
Term Detail
MP term:abnormal Leydig cell morphology
Synonym: abnormal Leydig cells
MP id: MP:0002786
Definition: any structural anomaly of the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH); Leydig cells are polyhedral in shape, display a large prominent nucleus, an eosinophilic cytoplasm and numerous lipid-filled vesicles
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland morphology
                        is-aabnormal sex gland morphology
                                is-aabnormal male reproductive gland morphology
                                        is-aabnormal testis morphology
                                                is-aabnormal seminiferous tubule morphology
                                                        is-aabnormal Leydig cell morphology [MP:0002786] (110 genotypes, 130 annotations)
                                                                is-aabnormal Leydig cell differentiation +
                                                                is-aabsent Leydig cells
                                                                is-aectopic Leydig cells
                                                                is-aLeydig cell atrophy
                                                                is-aLeydig cell hyperplasia
                                                                is-aLeydig cell hypertrophy
                                                                is-aLeydig cell hypoplasia
                                                        is-aabnormal peritubular myoid cell morphology +
                                                        is-aabnormal seminiferous tubule epithelium morphology +
                                                        is-aabnormal seminiferous tubule size +
                                                        is-adilated seminiferous tubules
                                                        is-aseminiferous tubule degeneration


mammalian phenotype
        is-areproductive system phenotype
                is-aabnormal reproductive system morphology
                        is-aabnormal male reproductive system morphology
                                is-aabnormal male genitalia morphology
                                        is-aabnormal internal male genitalia morphology
                                                is-aabnormal testis morphology
                                                        is-aabnormal seminiferous tubule morphology
                                                                is-aabnormal Leydig cell morphology [MP:0002786] (110 genotypes, 130 annotations)
                                                                        is-aabnormal Leydig cell differentiation +
                                                                        is-aabsent Leydig cells
                                                                        is-aectopic Leydig cells
                                                                        is-aLeydig cell atrophy
                                                                        is-aLeydig cell hyperplasia
                                                                        is-aLeydig cell hypertrophy
                                                                        is-aLeydig cell hypoplasia
                                                                is-aabnormal peritubular myoid cell morphology +
                                                                is-aabnormal seminiferous tubule epithelium morphology +
                                                                is-aabnormal seminiferous tubule size +
                                                                is-adilated seminiferous tubules
                                                                is-aseminiferous tubule degeneration


mammalian phenotype
        is-areproductive system phenotype
                is-aabnormal reproductive system morphology
                        is-aabnormal sex gland morphology
                                is-aabnormal male reproductive gland morphology
                                        is-aabnormal testis morphology
                                                is-aabnormal seminiferous tubule morphology
                                                        is-aabnormal Leydig cell morphology [MP:0002786] (110 genotypes, 130 annotations)
                                                                is-aabnormal Leydig cell differentiation +
                                                                is-aabsent Leydig cells
                                                                is-aectopic Leydig cells
                                                                is-aLeydig cell atrophy
                                                                is-aLeydig cell hyperplasia
                                                                is-aLeydig cell hypertrophy
                                                                is-aLeydig cell hypoplasia
                                                        is-aabnormal peritubular myoid cell morphology +
                                                        is-aabnormal seminiferous tubule epithelium morphology +
                                                        is-aabnormal seminiferous tubule size +
                                                        is-adilated seminiferous tubules
                                                        is-aseminiferous tubule degeneration

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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory