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Term Detail
MP term:abnormal neutrophil physiology
Synonym: abnormal neutrocyte physiology
Synonym: abnormal neutrophilic leucocyte physiology
Synonym: abnormal neutrophilic leukocyte physiology
Synonym: abnormal neutrophil leucocyte physiology
Synonym: abnormal neutrophil leukocyte physiology
Synonym: abnormal PMN physiology
Synonym: abnormal polymorphonuclear leucocyte physiology
Synonym: abnormal polymorphonuclear leukocyte physiology
Synonym: abnormal polymorphonuclear neutrophil physiology
Synonym: abnormal polynuclear neutrophilic leucocyte physiology
Synonym: abnormal polynuclear neutrophilic leukocyte physiology
Synonym: neutrophil dysfunction
MP id: MP:0002463
Definition: abnormal function of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal granulocyte physiology
                                                is-aabnormal basophil physiology
                                                is-aabnormal eosinophil physiology +
                                                is-aabnormal granulocyte chemotaxis +
                                                is-aabnormal mast cell physiology +
                                                is-aabnormal neutrophil physiology [MP:0002463] (244 genotypes, 295 annotations)
                                                        is-aimpaired neutrophil chemotaxis
                                                        is-aimpaired neutrophil phagocytosis
                                                        is-aimpaired neutrophil recruitment
                                                is-aimpaired granulocyte bactericidal activity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal granulocyte physiology
                                                is-aabnormal basophil physiology
                                                is-aabnormal eosinophil physiology +
                                                is-aabnormal granulocyte chemotaxis +
                                                is-aabnormal mast cell physiology +
                                                is-aabnormal neutrophil physiology [MP:0002463] (244 genotypes, 295 annotations)
                                                        is-aimpaired neutrophil chemotaxis
                                                        is-aimpaired neutrophil phagocytosis
                                                        is-aimpaired neutrophil recruitment
                                                is-aimpaired granulocyte bactericidal activity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal granulocyte physiology
                                                is-aabnormal basophil physiology
                                                is-aabnormal eosinophil physiology +
                                                is-aabnormal granulocyte chemotaxis +
                                                is-aabnormal mast cell physiology +
                                                is-aabnormal neutrophil physiology [MP:0002463] (244 genotypes, 295 annotations)
                                                        is-aimpaired neutrophil chemotaxis
                                                        is-aimpaired neutrophil phagocytosis
                                                        is-aimpaired neutrophil recruitment
                                                is-aimpaired granulocyte bactericidal activity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal granulocyte physiology
                                                is-aabnormal basophil physiology
                                                is-aabnormal eosinophil physiology +
                                                is-aabnormal granulocyte chemotaxis +
                                                is-aabnormal mast cell physiology +
                                                is-aabnormal neutrophil physiology [MP:0002463] (244 genotypes, 295 annotations)
                                                        is-aimpaired neutrophil chemotaxis
                                                        is-aimpaired neutrophil phagocytosis
                                                        is-aimpaired neutrophil recruitment
                                                is-aimpaired granulocyte bactericidal activity


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal innate immunity
                                is-aabnormal acute phase protein level +
                                is-aabnormal complement pathway +
                                is-aabnormal macrophage physiology +
                                is-aabnormal neutrophil physiology [MP:0002463] (244 genotypes, 295 annotations)
                                        is-aimpaired neutrophil chemotaxis
                                        is-aimpaired neutrophil phagocytosis
                                        is-aimpaired neutrophil recruitment
                                is-aabnormal NK cell physiology +

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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory