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Mammalian Phenotype Browser
Term Detail
MP term:abnormal professional antigen presenting cell physiology
Synonym: abnormal antigen presenting cell physiology
Synonym: antigen presenting cell dysfunction
MP id: MP:0002452
Definition: any functional anomaly of a cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal class switch recombination
                                is-aabnormal leukocyte physiology +
                                is-aabnormal professional antigen presenting cell physiology [MP:0002452] (2163 genotypes, 4400 annotations)
                                        is-aabnormal B cell physiology +
                                        is-aabnormal dendritic cell physiology +
                                        is-aabnormal macrophage physiology +
                                is-aabnormal somatic hypermutation frequency
                                is-aabnormal type I hypersensitivity reaction +
                                is-aabnormal type II hypersensitivity reaction +
                                is-aabnormal type III hypersensitivity reaction +
                                is-aabnormal type IV hypersensitivity reaction +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology +
                                is-aabnormal professional antigen presenting cell physiology [MP:0002452] (2163 genotypes, 4400 annotations)
                                        is-aabnormal B cell physiology +
                                        is-aabnormal dendritic cell physiology +
                                        is-aabnormal macrophage physiology +
                                is-aabnormal type IV hypersensitivity reaction +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal follicular dendritic cell physiology +
                                is-aabnormal leukocyte physiology +
                                is-aabnormal professional antigen presenting cell physiology [MP:0002452] (2163 genotypes, 4400 annotations)
                                        is-aabnormal B cell physiology +
                                        is-aabnormal dendritic cell physiology +
                                        is-aabnormal macrophage physiology +

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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory