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Mammalian Phenotype Browser
Term Detail
MP term:abnormal double-negative T cell morphology
Synonym: abnormal double negative T cell morphology
Synonym: CD4-CD8- T cell abnormalities
Synonym: double-negative T cell abnormalities
Synonym: double-negative T-cell abnormalities
MP id: MP:0002407
Definition: any structural anomaly of the subset of T cells found in the thymus that express neither CD4 nor CD8
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphopoiesis
                                                                        is-aabnormal T cell differentiation
                                                                                is-aabnormal CD4-positive T cell differentiation +
                                                                                is-aabnormal CD8-positive T cell differentiation
                                                                                is-aabnormal double-negative T cell morphology [MP:0002407] (307 genotypes, 368 annotations)
                                                                                        is-adecreased double-negative T cell number +
                                                                                        is-aincreased double-negative T cell number +
                                                                                is-aabnormal double-positive T cell morphology +
                                                                                is-aabnormal gamma-delta T cell differentiation
                                                                                is-aabnormal T cell activation +
                                                                                is-aabnormal T cell receptor V(D)J recombination +
                                                                                is-aabnormal T cell selection +
                                                                                is-aabnormal T-helper 17 cell differentiation
                                                                                is-aarrested T cell differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal T cell morphology
                                                                        is-aabnormal T cell differentiation
                                                                                is-aabnormal CD4-positive T cell differentiation +
                                                                                is-aabnormal CD8-positive T cell differentiation
                                                                                is-aabnormal double-negative T cell morphology [MP:0002407] (307 genotypes, 368 annotations)
                                                                                        is-adecreased double-negative T cell number +
                                                                                        is-aincreased double-negative T cell number +
                                                                                is-aabnormal double-positive T cell morphology +
                                                                                is-aabnormal gamma-delta T cell differentiation
                                                                                is-aabnormal T cell activation +
                                                                                is-aabnormal T cell receptor V(D)J recombination +
                                                                                is-aabnormal T cell selection +
                                                                                is-aabnormal T-helper 17 cell differentiation
                                                                                is-aarrested T cell differentiation


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukopoiesis
                                                is-aabnormal lymphopoiesis
                                                        is-aabnormal T cell differentiation
                                                                is-aabnormal CD4-positive T cell differentiation +
                                                                is-aabnormal CD8-positive T cell differentiation
                                                                is-aabnormal double-negative T cell morphology [MP:0002407] (307 genotypes, 368 annotations)
                                                                        is-adecreased double-negative T cell number +
                                                                        is-aincreased double-negative T cell number +
                                                                is-aabnormal double-positive T cell morphology +
                                                                is-aabnormal gamma-delta T cell differentiation
                                                                is-aabnormal T cell activation +
                                                                is-aabnormal T cell receptor V(D)J recombination +
                                                                is-aabnormal T cell selection +
                                                                is-aabnormal T-helper 17 cell differentiation
                                                                is-aarrested T cell differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphopoiesis
                                                                is-aabnormal T cell differentiation
                                                                        is-aabnormal CD4-positive T cell differentiation +
                                                                        is-aabnormal CD8-positive T cell differentiation
                                                                        is-aabnormal double-negative T cell morphology [MP:0002407] (307 genotypes, 368 annotations)
                                                                                is-adecreased double-negative T cell number +
                                                                                is-aincreased double-negative T cell number +
                                                                        is-aabnormal double-positive T cell morphology +
                                                                        is-aabnormal gamma-delta T cell differentiation
                                                                        is-aabnormal T cell activation +
                                                                        is-aabnormal T cell receptor V(D)J recombination +
                                                                        is-aabnormal T cell selection +
                                                                        is-aabnormal T-helper 17 cell differentiation
                                                                        is-aarrested T cell differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal T cell morphology
                                                                is-aabnormal T cell differentiation
                                                                        is-aabnormal CD4-positive T cell differentiation +
                                                                        is-aabnormal CD8-positive T cell differentiation
                                                                        is-aabnormal double-negative T cell morphology [MP:0002407] (307 genotypes, 368 annotations)
                                                                                is-adecreased double-negative T cell number +
                                                                                is-aincreased double-negative T cell number +
                                                                        is-aabnormal double-positive T cell morphology +
                                                                        is-aabnormal gamma-delta T cell differentiation
                                                                        is-aabnormal T cell activation +
                                                                        is-aabnormal T cell receptor V(D)J recombination +
                                                                        is-aabnormal T cell selection +
                                                                        is-aabnormal T-helper 17 cell differentiation
                                                                        is-aarrested T cell differentiation


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukopoiesis
                                        is-aabnormal lymphopoiesis
                                                is-aabnormal T cell differentiation
                                                        is-aabnormal CD4-positive T cell differentiation +
                                                        is-aabnormal CD8-positive T cell differentiation
                                                        is-aabnormal double-negative T cell morphology [MP:0002407] (307 genotypes, 368 annotations)
                                                                is-adecreased double-negative T cell number +
                                                                is-aincreased double-negative T cell number +
                                                        is-aabnormal double-positive T cell morphology +
                                                        is-aabnormal gamma-delta T cell differentiation
                                                        is-aabnormal T cell activation +
                                                        is-aabnormal T cell receptor V(D)J recombination +
                                                        is-aabnormal T cell selection +
                                                        is-aabnormal T-helper 17 cell differentiation
                                                        is-aarrested T cell differentiation

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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory