| MP term: | abnormal type II pneumocyte morphology |
| Synonym: | abnormal AT2 morphology |
| Synonym: | abnormal ATII morphology |
| Synonym: | abnormal Cuboidal type II cell morphology |
| Synonym: | abnormal granular pneumocytes morphology |
| Synonym: | abnormal Great alveolar cells morphology |
| Synonym: | abnormal Lung type 2 cells morphology |
| Synonym: | abnormal Lung type II cells morphology |
| Synonym: | abnormal TII morphology |
| Synonym: | abnormal type 2 alveolar epithelial cells morphology |
| Synonym: | abnormal type 2 alveolocytes morphology |
| Synonym: | abnormal type 2 pneumocyte morphology |
| Synonym: | abnormal type II alveolar epithelial cells morphology |
| Synonym: | abnormal type II alveolocytes morphology |
| Synonym: | abnormal type II cells morphology |
| Synonym: | abnormal type II pneumocytes morphology |
| Synonym: | abnormal type II pneumonocytes morphology |
| MP id: | MP:0002275 |
| Definition: | any structural anomaly of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
respiratory system phenotypeabnormal respiratory system morphologyabnormal lung morphologyabnormal lung epithelium morphologyabnormal pulmonary alveolus epithelium morphologyabnormal pulmonary alveolus epithelial cell morphologyabnormal type I pneumocyte morphology +abnormal type II pneumocyte morphology [MP:0002275] (70 genotypes, 111 annotations)abnormal alveolar lamellar body morphology +decreased type II pneumocyte number +increased type II pneumocyte numberrespiratory system phenotypeabnormal respiratory system morphologyabnormal lung morphologyabnormal pulmonary alveolar system morphologyabnormal pulmonary acinus morphologyabnormal pulmonary alveolus morphologyabnormal pulmonary alveolus epithelium morphologyabnormal pulmonary alveolus epithelial cell morphologyabnormal type I pneumocyte morphology +abnormal type II pneumocyte morphology [MP:0002275] (70 genotypes, 111 annotations)abnormal alveolar lamellar body morphology +decreased type II pneumocyte number +increased type II pneumocyte numberrespiratory system phenotypeabnormal respiratory system morphologyabnormal lung morphologyabnormal pulmonary alveolar system morphologyabnormal pulmonary alveolar parenchyma morphologyabnormal pulmonary alveolus epithelial cell morphologyabnormal type I pneumocyte morphology +abnormal type II pneumocyte morphology [MP:0002275] (70 genotypes, 111 annotations)abnormal alveolar lamellar body morphology +decreased type II pneumocyte number +increased type II pneumocyte numberrespiratory system phenotypeabnormal respiratory system morphologyabnormal respiratory epithelium morphologyabnormal lung epithelium morphologyabnormal pulmonary alveolus epithelium morphologyabnormal pulmonary alveolus epithelial cell morphologyabnormal type I pneumocyte morphology +abnormal type II pneumocyte morphology [MP:0002275] (70 genotypes, 111 annotations)abnormal alveolar lamellar body morphology +decreased type II pneumocyte number +increased type II pneumocyte numberMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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