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Mammalian Phenotype Browser
Term Detail
MP term:abnormal astrocyte morphology
Synonym: abnormal astrocytes morphology
Synonym: abnormal astrocytic glia morphology
Synonym: abnormal astroglial cell morphology
Synonym: abnormal astroglia morphology
MP id: MP:0002182
Definition: any structural anomaly of the large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord; astrocytes are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier; astrocytes regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal glial cell morphology
                                is-aabnormal CNS glial cell morphology
                                        is-aabnormal astrocyte morphology [MP:0002182] (364 genotypes, 387 annotations)
                                                is-aabnormal astrocyte number +
                                                is-aabnormal pituicyte morphology
                                        is-aabnormal microglial cell morphology +
                                        is-aabnormal Muller cell morphology
                                        is-aabnormal oligodendrocyte morphology +
                                        is-aabnormal radial glial cell morphology
                                        is-aectopic Bergmann glia cells

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory