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Mammalian Phenotype Browser
Term Detail
MP term:abnormal neural tube morphology/development
Synonym: abnormal neural tube morphology
Synonym: central nervous system: neural tube defects
Synonym: neural tube defects
Synonym: neural tube dysplasia
MP id: MP:0002151
Alternate id: MP:0000922, Fyler:4339
Definition: any structural anomaly of or development of the hollow epithelial tube found on the dorsal side of the vertebrate embryo that develops into the central nervous system (i.e. brain and spinal cord)
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal embryonic tissue morphology
                                is-aabnormal anterior definitive endoderm morphology
                                is-aabnormal branchial arch morphology +
                                is-aabnormal branchial pouch morphology +
                                is-aabnormal egg cylinder morphology +
                                is-aabnormal embryonic cloaca morphology +
                                is-aabnormal gonadal ridge morphology +
                                is-aabnormal head fold morphology +
                                is-aabnormal head mesenchyme morphology +
                                is-aabnormal intraembryonic coelom morphology
                                is-aabnormal limb bud morphology +
                                is-aabnormal mesenchyme morphology +
                                is-aabnormal mesonephros morphology +
                                is-aabnormal neural fold morphology +
                                is-aabnormal neural plate morphology +
                                is-aabnormal neural tube morphology/development [MP:0002151] (1055 genotypes, 1500 annotations)
                                        is-aabnormal embryonic neuroepithelium morphology +
                                        is-aabnormal floor plate morphology +
                                        is-aabnormal lamina terminalis morphology +
                                        is-aabnormal neural crest morphology +
                                        is-aabnormal neural tube closure +
                                        is-aabnormal neural tube mantle layer morphology +
                                        is-aabnormal neural tube marginal layer morphology
                                        is-aabnormal neural tube ventricular layer morphology
                                        is-aabnormal neuromere morphology +
                                        is-aabnormal neuropore morphology +
                                        is-aabnormal roof plate morphology +
                                        is-acaudal rachischisis
                                        is-acraniorachischisis
                                        is-akinked neural tube
                                        is-aneural tube degeneration
                                        is-awavy neural tube
                                is-aabnormal notochord morphology +
                                is-aabnormal pleuropericardial membrane morphology +
                                is-aabnormal pluripotent precursor cell morphology/development +
                                is-aabnormal rostral-caudal body axis extension
                                is-aabnormal septum transversum morphology
                                is-aabnormal somite development +
                                is-aabnormal tail bud morphology +
                                is-aabnormal tail fold morphology
                                is-aabnormal triploblastic development +
                                is-aabnormal urogenital fold morphology
                                is-aabnormal urorectal septum morphology
                                is-adisorganized embryonic tissue


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal nervous system development
                                is-aabnormal brain development +
                                is-aabnormal CNS synapse formation +
                                is-aabnormal embryonic/fetal subventricular zone morphology +
                                is-aabnormal neural plate morphology +
                                is-aabnormal neural tube morphology/development [MP:0002151] (1055 genotypes, 1500 annotations)
                                        is-aabnormal embryonic neuroepithelium morphology +
                                        is-aabnormal floor plate morphology +
                                        is-aabnormal lamina terminalis morphology +
                                        is-aabnormal neural crest morphology +
                                        is-aabnormal neural tube closure +
                                        is-aabnormal neural tube mantle layer morphology +
                                        is-aabnormal neural tube marginal layer morphology
                                        is-aabnormal neural tube ventricular layer morphology
                                        is-aabnormal neuromere morphology +
                                        is-aabnormal neuropore morphology +
                                        is-aabnormal roof plate morphology +
                                        is-acaudal rachischisis
                                        is-acraniorachischisis
                                        is-akinked neural tube
                                        is-aneural tube degeneration
                                        is-awavy neural tube
                                is-aabnormal neuron differentiation +
                                is-aabnormal neuronal stem cell morphology
                                is-aabnormal vestibulocochlear ganglion morphology +
                                is-aanencephaly +

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory